From: Does conventional morphological evaluation still play a role in predicting blastocyst formation?
Variable | Training set | Validation set |
---|---|---|
Cycles, n | 13,657 | 1956 |
Female age, year | 30 [28-33] | 31 [29-34] |
Male age, year | 32 [29-35] | 32 [30–36] |
GnRH analogues | ||
Agonist | 12,118(88.7) | 1605(82.1) |
Non-agonist | 1539(11.3) | 351(17.9) |
Insemination protocol | ||
IVF | 9948(72.8) | 1450(74.1) |
ICSI | 3709(27.2) | 506(25.9) |
TESA/PESA + ICSI | 643(4.7) | 72(3.7) |
Female height, cm | 158 [155–162] | 158 [155–162] |
Female weight, kg | 53 [48–57] | 53 [49–57] |
Female BMI, kg/m2 | 21 [19.4–22.6] | 21.33 [19.78–22.77] |
Female basal FSH, IU/l | 6.71 [5.76–7.88] | 7.68 [6.4325–9.17] |
Female basal LH, IU/l | 4.41 [3.29–5.9] | 4.55 [3.4–6.25] |
Female basal PRL, ng/ml | 13.83 [10.03–19.11] | 14.74 [10.8725–20.6175] |
Female basal E2, pg/ml | 41 [30–55] | 42 [31–57] |
Female basal T, ng/ml | 0.42 [0.3–0.56] | 0.42 [0.3–0.55] |
Basal AFC | 11 [8-15] | 10 [7-15] |
Gonadotropin dose, IU | 2250 [1800–2700] | 2250 [1800–2700] |
Gonadotropin duration, IU | 12 [10-13] | 12 [10-13] |
HMG dose, IU | 1987.5 [937.5–2475] | 1950 [675–2550] |
HMG duration, IU | 11 [8-12] | 11 [5-13] |
Starting dose, IU | 225 [150–225] | 187.5 [150–225] |
FSH on the day of stimulation, IU/l | 2.34 [1.59–3.58] | 2.74 [1.88–4.64] |
LH on the day of stimulation, IU/l | 0.81 [0.58–1.17] | 0.79 [0.55–1.2875] |
E2 on the day of stimulation, pg/ml | 20 [12-30] | 23 [14-35] |
E2 on the day of triggering, pg/ml | 3845 [2390–5198] | 3231.5 [1850.75–4754.5] |
LH on the day of triggering, IU/l | 0.69 [0.41–1.13] | 0.7 [0.39–1.29] |
P on the day of triggering, ng/ml | 1.03 [0.71–1.46] | 0.86 [0.6–1.2] |
Oocyte yield | 11 [8-16] | 10 [6-13] |
Maturation rate of oocytes,% | 92.8 [84.6–100] | 92.85 [83.33–100] |
Embryos subjected to blastocyst culture | 6 [4-9] | 5 [3-8] |
Good quality embryos | 5 [3-7] | 4 [2-6] |
Cycles with no blastocyst formed, % | 1008(7.4) | 213(10.9) |
Blasocyst formed, per cycle | 3 [2-6] | 3 [1-5] |
Blastulation rate, per cycle | 58.33 [37.5–75] | 61.54 [38.46–81.82] |