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Fig. 2 | Reproductive Biology and Endocrinology

Fig. 2

From: Rapamycin improves the quality and developmental competence of mice oocytes by promoting DNA damage repair during in vitro maturation

Fig. 2

Effects of IVM with 10 nM rapamycin on the quality of MII oocytes. A The immunofluorescence images of normal and abnormal spindle and chromosome of IVM oocytes. Scale bar, 25 μm. B The percentages of oocytes with chromosome aberration. C The percentages of oocytes with abnormal spindle morphology. D The immunofluorescence images showing JC-1 staining intensity in oocytes matured in different media. Scale bar, 75 μm. E The relative levels of MMP (red/green fluorescence intensity) in oocytes from both groups. All data were expressed as mean ± SEM from three independent experiments, involving totally 205 oocytes. *P < 0.05

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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