Fig. 1

Subsequent development of PA embryos from control and 10 nM rapamycin groups. A The status of PA embryos in both groups at 0 h, 24 h, 48 h, and 108 h of culture. The blastocysts were indicated with black arrows. Scale bar, 50 μm. B The comparison of cleavage rates and blastocyst formation rates of PA embryos from both groups. All data were expressed as mean ± SEM from three independent experiments, involving totally 126 oocytes. Con: control; Rapa: rapamycin. *P < 0.05