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Table 2 Clinical characteristics and outcomes of the two groups

From: Comparative analyses in transcriptome of human granulosa cells and follicular fluid micro-environment between poor ovarian responders with conventional controlled ovarian or mild ovarian stimulations

 

Mild group

COS group

P value

Age (years)

39.19 ± 3.25

38.05 ± 3.72

0.264

AMH (ng/ml)

0.61 ± 0.30

0.77 ± 0.22

0.053

BMI (kg/m2)

23.08 ± 2.66

21.70 ± 1.92

0.051

Basal FSH (U/L)

8.68 ± 2.90

9.67 ± 5.27

0.415

Basal E2 (pg/ml)

54.23 ± 21.28

48.38 ± 18.75

0.326

Basal LH (U/L)

4.18 ± 1.42

4.32 ± 2.06

0.783

Duration of stimulation (days)

5.93 ± 1.64

10.67 ± 1.49

 < 0.001a

Total gonadotropin/cycle (IU)

867.59 ± 241.37

3152.38 ± 408.19

 < 0.001a

Serum E2 level on trigger day (pg/ml)

522.33 ± 325.11

1205.13 ± 504.42

 < 0.001a

Serum LH level on trigger day (U/L)

5.94 ± 5.43

2.91 ± 1.52

0.017a

Serum P level on trigger day (ng/ml)

0.47 ± 0.35

0.79 ± 0.41

0.006a

No. of oocytes retrieved

3.48 ± 1.40

5.29 ± 3.50

0.018a

No. of oocytes in metaphase II

2.70 ± 1.43

3.29 ± 2.70

0.342

Rate of oocytes in metaphase II (%)

77.66

62.16

0.017 a

No. of 2PN oocytes

2.22 ± 1.28

3.14 ± 2.59

0.114

No. of transferrable embryos

2.00 ± 1.24

2.48 ± 2.02

0.319

No. of good-quality embryos

1.83 ± 1.24

1.76 ± 1.68

0.881

Rate of good-quality embryos (%)

75.86

57.69

0.043 a

  1. Values expressed as means ± SD or percentage. AMH anti-müllerian hormone, BMI body mass index, FSH follicle stimulating hormone, E2 estradiol, LH luteinizing hormone, P progesterone; 2PN 2 pronuclei
  2. aResults are significantly different between the two groups