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Table 5 Oocyte morphologic quality, by PCOS phenotype

From: Polycystic ovary syndrome phenotype does not have impact on oocyte morphology

  PCOS A
N = 41
PCOS C
N = 31
PCOS D
N = 37
p value Adjusted p
Number of MII oocytes 602 462 432
Normal oocytes, n (%) 212
(35.2 [31.5 to 39.1])
119
(25.8 [21.9 to 29.9])
147
(34.0 [29.7 to 38.6])
0.031 0.13
Fragmented or abnormal FPB, n (%) 299
(49.7 [45.7 to 53.7])
245
(53.0 [48.5 to 57.5])
241
(55.8 [51.1 to 60.4])
0.16 0.15
Abnormal zona pellucida, n (%) 8
(1.3 [0.7 to 2.6])
6
(1.3 [0.6 to 2.9])
3
(0.7 [0.2 to 2.1])
0.60 0.75
Large perivitelline space, n (%) 49
(8.1 [6.2 to 10.6])
56
(12.1 [9.4 to 15.4])
29
(6.7 [4.7 to 9.5])
0.36 0.34
Material in perivitelline space, n (%) 68
(11.3 [9.0 to 14.1])
52
(11.3 [8.9 to 14.5])
41
(9.5 [7.1 to 12.6])
0.89 0.80
Abnormal shape of oocyte, n (%) 19
(3.2 [2.0 to 4.9])
14
(3.0 [1.8 to 5.1])
9
(2.1 [1.1 to 4.0])
0.41 0.39
Granular cytoplasm, n (%) 21
(3.5 [2.3 to 5.3])
16
(3.5 [2.1 to 5.6])
16
(3.7 [2.3 to 6.0])
0.92 0.81
Intracytoplasmic vacuoles, n (%) 12
(2.0 [1.1 to 3.5])
15
(3.3 [2.0 to 5.3])
3
(0.7 [0.2 to 2.1])
0.049 0.053
AOQI, mean ± SDa 0.76 [0.68 to 0.85] 0.85 [0.72 to 0.98] 0.75 [0.64 to 0.86] 0.29 0.40
average MOMS per cycle, mean ± SDa 1.31 [1.04 to 1.46] 1.30 [1.10 to 1.50] 1.27 [1.08 to 1.46] 0.80 0.83
  1. Values are quoted as the mean [95%CI] or n (% [95%CI]). The p value was adjusted for the woman’s age, BMI and current smoking status, the type of COH protocol, and the total dose of FSH
  2. Abbreviations: MII metaphase II, FPB first polar body, ZP zona pellucida, AOQI average oocyte quality index, MOMS metaphase II oocyte morphologic score
  3. aThe AOQI score considers all the oocyte morphologic abnormalities per cycle (Sigala et al., 2015 [36]), while the MOMS takes account of the morphologic abnormalities per oocyte. However, the MOMS was averaged by cycle here, in order to compare the groups (Rienzi et al., 2008 [37])