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Table 2 Effect of ICA on body weight, blood glucose, insulin levels and insulin resistance index in diabetic rats

From: Icariin improves testicular dysfunction via enhancing proliferation and inhibiting mitochondria-dependent apoptosis pathway in high-fat diet and streptozotocin-induced diabetic rats

Group BW (g) FBG (mmol L−1) FINS
(uIU mL−1)
IRI
Before After Before After
Control 341.2 ± 7.644 402.5 ± 8.705a 6.150 ± 0.5296a 4.817 ± 0.1833a 73.89 ± 15.00a 20.96 ± 0.940a
T2DM 316.7 ± 17.09 232.8 ± 26.64b 22.07 ± 0.7843b 27.48 ± 0.9630b 96.26 ± 40.07b 188.5 ± 51.80b
Metformin 321.2 ± 5.350 350.0 ± 31.54c 18.10 ± 0.5125b 5.000 ± 0.4359a 188.9 ± 82.10c 39.72 ± 19.31c
ICA 340.7 ± 13.20 261.6 ± 11.43b 22.43 ± 0.7796b 7.650 ± 2.0840a 118.2 ± 13.62b 23.24 ± 9.770a
  1. In each column, values assigned with different superscript lowercases (letters) indicate significant difference (P < 0.05). In each row of BW and FBG, values assigned with different superscript symbols (diamond symbols) also indicate significant difference (P < 0.05). BW body weight; FBG fasting blood glucose; FINS fasting insulin; IRI insulin resistance index