Evaluation of GnRH antagonist pretreatment before ovarian stimulation in a GnRH antagonist protocol in normal ovulatory women undergoing IVF/ICSI: a randomized controlled trial

Table 2 Stimulation characteristics and embryological data

Variable	study group	control group	p- value
No. of follicles ≥14 mm at trigger day	8.0(6.0–11.0)	9.0(7.0–11.0)	0.568
Follicle output rate ^b(%)	77.4(53.5–100.0)	80.4(54.0–100.0)	0.764
No. of oocytes retrieved (n)	9.5(8.0–13.0)	11.0(7.0–14.8)	0.469
No. of MII oocytes^c(n)	7.0(6.0–11.0)	9(5.3–12.0)	0.485
MII oocyte rate(%)	80.2(71.4–100.0)	82.8(72.8–100.0)	0.991
No. of 2PN oocytes (n)	6.0(4.0–8.0)	6.5(4.0–9.0)	0.365
No. of transferable embryos (n)	5.5(4.0–7.8)	6.0(4.0–8.0)	0.236
No. of good quality embryos(n)^d	2.0(1.0–4.0)	2.0(1.0–4.0)	0.708
No. of frozen embryos (n)	2.0(0.0–4.0)	2.0(1.0–4.0)	0.502

Note: Data are presented as the median and interquartile range (IQR)
^aControl group used as a reference
^bFollicular output rate determined by the ratio of the preovulatory follicle (14–22 mm) count on the HCG trigger day ×100/the small antral follicle (3–8 mm) count at baseline,
^cMII-metaphase II
^dGood-quality embryos included day-3 and day-5/6 high-quality embryos (according to our centre’s quality embryo scoring standards, day-3 embryos that were considered were grade 1–2 with 7–9 blastomeres and < 20% fragmentation [21]; blastocysts that were considered were at least at expansion stage 3, had an inner cell mass score of A or B, and had a trophectoderm score of A or B on day 5)

ISSN: 1477-7827