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Table 2 Results of histopathological examination

From: The ameliorative effect of ellagic acid on di-(2-ethylhexyl) phthalate-induced testicular structural alterations, oxidative stress, inflammation and sperm damages in adult mice

 

NS

DEHP

DEHP + EA 25

DEHP + EA 50

DEHP + EA 100

Tunica albuginea height (μm)

45.4 ± 5.2

19.1 ± 0.9 a

21.1 ± 4.1 a

24.5 ± 1.2 a

43.6 ± 5.4 b, c, d

Seminiferous tubular diameter (μm)

173.7 ± 34.1

80.0 ± 15.31 a

97.0 ± 9.1 a

137.0 ± 21.91 b, c

151.6 ± 32.7 b, c

Seminiferous luminal diameter (μm)

72.3 ± 6.1

41.6 ± 11.9 a

47.0 ± 17.7 a

73.5 ± 8.6 b, c

88.9 ± 10.7 b, c

Seminiferous epithelial height (μm)

71.3 ± 5.4

16.4 ± 1.8 a

28.9 ± 2.7 a, b

46.4 ± 2.78 a, b, c, d

63.9 ± 3.2 a, b, c, d

Number of spermatogonia /tubule

31.9 ± 3.6

11.1 ± 2.1 a

23.3 ± 2.3 a, b

27.4 ± 3.1 a, b, c, d

31.6 ± 3.7 a, b, c, d

Number of primary spermatocyte /tubule

45.3 ± 5.7

16.8 ± 3.6 a

22.7 ± 4.2 a

33.2 ± 4.8 a, b, c

35.3 ± 5.1 a, b, c

Number of early spermatid /tubule

53.9 ± 6.4

22.5 ± 3.3 a

33.1 ± 3.7 a, b

38.4 ± 4.2 a, b

43.2 ± 5.2 a, b, c

Number of late spermatid /tubule

59.3 ± 6.5

30.8 ± 4.8 a

43.7 ± 5.3 a, b

48.1 ± 5.5 a, b

53.7 ± 6.1 b, c

  1. Values are means ± S.D. (n = 7)
  2. ap<0.05 as compared to control group
  3. bp<0.05 as compared to DEHP group
  4. cp<0.05 as compared to DEHP+ EA 25 group
  5. dp<0.05 as compared to DEHP+ EA 50 group