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Table 4 Correlation analysis between the concentration of oxidized lipid metabolites and related parameters

From: UHPLC-MS-MS analysis of oxylipins metabolomics components of follicular fluid in infertile individuals with diminished ovarian reserve

Metabolites(ng/ml) R/P AGE FSH AMH AFC OR MII FER HQE
20-HDoHE R -0.120 -0.555** 0.426** 0.581** 0.446** 0.457** 0.400* 0.250
P 0.461 0.000 0.006 0.000 0.004 0.003 0.010 0.120
±5-iso PGF2α-VI R -0.175 -0.455** 0.361* 0.508** 0.361* 0.341 0.273 0.103
P 0.286 0.004 0.024 0.001 0.024 0.052 0.093 0.531
12S-HHTrE R -0.101 -0.303 0.365* 0.252 0.347* 0.385* 0.361* 0.002
P 0.535 0.057 0.021 0.117 0.028 0.014 0.022 0.989
15-deoxy-Δ12,14-PGJ2 R 0.024 -0.346* 0.264 0.298 0.144 0.147 0.096 -0.266
P 0.882 0.029 0.099 0.062 0.376 0.365 0.556 0.097
1a,1b-dihomo PGE2 R -0.147 -0.347* 0.547** 0.425** 0.463** 0.495** 0.497** 0.151
P 0.367 0.028 0.000 0.006 0.003 0.001 0.001 0.351
1a,1b-dihomo PGF2α R 0.052 -0.148 0.259 0.296 0.223 0.276 0.287 0.056
P 0.749 0.361 0.107 0.063 0.166 0.084 0.073 0.730
20-COOH-AA R -0.022 -0.353* 0.390* 0.362* 0.393* 0.414** 0.425** 0.339*
P 0.892 0.025 0.013 0.022 0.012 0.008 0.006 0.032
20-HETE R 0.191 -0.386 0.327 0.447 0.510 0.436 0.412 -0.220
P 0.494 0.156 0.234 0.095 0.052 0.104 0.128 0.431
8S,15S-DiHETE R -0.023 -0.241 0.509** 0.564** 0.452** 0.377* 0.356* 0.099
P 0.889 0.145 0.001 0.000 0.004 0.020 0.028 0.553
PGA2 R -0.149 -0.504** 0.511** 0.503** 0.408* 0.424* 0.373* -0.192
P 0.408 0.003 0.002 0.003 0.019 0.014 0.033 0.284
PGD2 R -0.187 -0.551* 0.009 0.385 0.374 0.482* 0.463* -0.168
P 0.442 0.015 0.972 0.104 0.115 0.037 0.046 0.492
PGE1 R -0.178 -0.481** 0.559** 0.512** 0.442** 0.437** 0.405* -0.058
P 0.278 0.002 0.000 0.001 0.005 0.005 0.011 0.726
PGF1α R -0.085 -0.323 0.278 0.297 0.128 0.131 0.148 -0.287
P 0.644 0.071 0.124 0.099 0.485 0.475 0.418 0.111
PGF2α R -0.162 -0.288 0.383* 0.357* 0.344* 0.414** 0.404* -0.074
P 0.319 0.072 0.015 0.024 0.030 0.008 0.010 0.649
PGJ2 R -0.100 -0.330 0.071 0.339 0.014 0.196 0.025 -0.422
P 0.745 0.271 0.817 0.257 0.964 0.520 0.936 0.151
  1. P, P-value,**P<0.01,*P<0.05; AGE, age; FSH, follicle stimulating hormone; AMH, anti-Mullerian hormone; AFC, antral follicle count; OR, number of oocytes retrieved; MII, number of MII oocytes; FER, number of fertilizations, HQE, number of high-quality embryos
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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