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Table 5 Fetal or neonatal Outcomes, According to Study Group

From: Maternal and infant outcomes during the COVID-19 pandemic: a retrospective study in Guangzhou, China

Outcomes

24 January – 31 March 2020

24 January – 31 March 2019

P Value

Median gestational age at delivery (Mean ± SD) — wk

39.26 ± 1.42 (n = 589)

39.08 ± 1.63 (n = 733)

0.04*

Full-term birth — no./total no. (%)

560/589 (95.08)

681/733 (92.91)

0.77

Premature birth — no./total no. (%)

29/589 (4.92)

51/733 (6.96)

0.15

Median birth weight (Mean ± SD) — kg

3.21 ± 0.43 (n = 589)

3.22 ± 1.32 (n = 733)

0.86

Median birth length (Mean ± SD) — cm

49.64 ± 1.81 (n = 589)

49.45 ± 2.15 (n = 733)

0.11

Low birth weight infant

13/589 (2.21)

19/733 (2.60)

0.66

Adverse fetal

7/589 (1.19)

11/733 (1.50)

0.63

Adverse neonatal outcomes — no./total no. (%)

   

Admission to NICU

122/589 (20.71)

157/733 (21.42)

0.80

Infection

27/589 (4.58)

59/733 (8.05)

0.02*

Shock

1/589 (0.17)

4/733 (0.55)

0.27

Sepsis

1/589 (0.17)

5/733 (0.68)

0.17

Apgar score < 7 after 1 min

10/589 (1.70)

20/733 (2.73)

0.22

Asphyxia

1/589 (0.17)

1/733 (0.14)

0.88

NRDS

5/589 (0.85)

11/733 (1.50)

0.29

Patent foramen ovale

21/589 (3.57)

44/733 (6.00)

 < 0.001***

Patent ductus arteriosus

14/589 (2.38)

17/733 (2.32)

0.95

Macrosomia

11/589 (1.87)

25/733 (3.41)

0.10

Myocardial damage

43/589 (7.30)

60/733 (8.19)

0.58

Neonatal hyperbilirubinemia

66/589 (11.21)

95/733 (13.00)

0.39

Hypoalbuminemia

18/589 (3.06)

33/733 (4.5)

0.19

Hypocalcemia

11/589 (1.87)

24/733 (3.27)

0.12

25-hydroxyvitamin D deficiency

16/589 (2.72)

1/733 (0.14)

 < 0.001***

Zinc deficiency

46/589 (7.81)

20/733 (2.73)

 < 0.001***

Neonatal polycythemia

8/589 (1.36)

3/733 (0.41)

0.06

G6PD deficiency

3/589 (0.51)

2/733 (0.27)

0.49

Caput succedaneum

27/589 (4.58)

26/733 (3.55)

0.36

  1. Differences between the groups were assessed with the use of the Mann–Whitney U test for gestational age; the use of the t test for full-term birth and premature birth; the use of the chi-square test for other test index. *p < 0.05, ***p < 0.001. NICU: neonatal intensive care unit; NRDS: neonatal respiratory distress syndrome; G6PD: Glucose 6-phosphate dehydrogenase