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Table 2 Outcomes with definitions of the inculded studies

From: GnRH agonist and hCG (dual trigger) versus hCG trigger for follicular maturation: a systematic review and meta-analysis of randomized trials

Author (year) Outcomes reported Primary outcome Outcomes not reported Outcomes definition in each study
Haas et al. (2020) [14] Number of mature oocytes; total number of oocytes, 2PN zygotes, embryo number, clinical pregnancy rate, implantation rate, live birth rate Number of mature oocytes Ongoing pregnancy rate Number of mature oocytes: number of MII oocytes. Other outcomes were not defined.
Mahajan et al. (2016) [21] Number of mature oocytes; total number of oocytes, 2PN zygotes; usable embryos Number of mature oocytes; usable embryos Ongoing pregnancy rate, clinical pregnancy rate, implantation rate, live birth rate Usable embryos: embryos good for transfer and cryopreservation. Other outcomes were not defined.
Ali et al. (2020) [13] Number of mature oocytes; total number of oocytes; number of Grade 1 embryos; fertilization rate (without the exact fertilizaton number); implantation rate (without the exact sac number and transferred embryo number); clinical pregnancy rate; live birth rate Number of mature oocytes Ongoing pregnancy rate Number of mature oocytes: number of MII oocytes; fertilization rate: the number of the fertilized oocytes divided by the total number of the retrieved oocytes per 100; implantation rate: total number of the sacs divided by the total number of the transferred embryos per 100; clinical pregnancy rate: the number of the cases with at least one sac in or out the uterus divided by the cycles initiated per 100; live birth rate: total number of the cases with at least one baby born after 24 weeks of gestation divided by the total number of the cycles initiated per 100.
Schachter et al. (2008) [24] Total number of oocytes; usable embryos; ongoing pregnancy rate; clinical pregnancy rate; implantation rate Not mentioned Number of mature oocytes; 2PN zygotes; live birth rate Implantation rate: number of gestational sacs per embryo transferred. Other outcomes were not defined.
Haas et al. (2019) [19] Total number of oocytes; 2PN zygotes; ongoing pregnancy rate Total number of oocytes, top-quality embryo Number of mature oocytes, clinical pregnancy rate, implantation rate, live birth rate, usable embryos Ongoing pregnancy: visualization of a gestational sac and fetal cardiac activity on transvaginal ultrasound. Other outcomes were not defined.
Eftekhar et al. (2017) [20] Number of mature oocytes; total number of oocytes, usable embryos; implantation number, clinical and ongoing pregnancy Clinical pregnancy 2PN zygotes, live birth rate No definition of outcomes
Kim et al. (2014) [22] Number of mature oocytes; total number of oocytes, 2PN zygotes, top-quality embryo, clinical pregnancy, implantation rate, live birth rate, severe OHSS Not mentioned Ongoing pregnancy rate, usable embryos Clinical pregnancy: increased serum β-hCG concentration. Other outcomes were not defined.
Decleer et al. (2014) [23] Number of mature oocytes; total number of oocytes, 2PN zygotes; Implantation rate; ongoing pregnancy rate Number of mature oocytes Clinical pregnancy rate, live birth rate, usable embryos Number of mature oocytes: number of MII oocytes. Implantation rate: mean number of foetal sacs per embryo transferred. Ongoing pregnancy: confirmed by ultrasound 23 days after embryo transfer. Other outcomes were not defined.
  1. Abbreviations: 2PN two pronuclei, OHSS ovarian hyperstimulation syndrome