Table 2 Outcomes with definitions of the inculded studies
Author (year) | Outcomes reported | Primary outcome | Outcomes not reported | Outcomes definition in each study |
|---|---|---|---|---|
Haas et al. (2020) [14] | Number of mature oocytes; total number of oocytes, 2PN zygotes, embryo number, clinical pregnancy rate, implantation rate, live birth rate | Number of mature oocytes | Ongoing pregnancy rate | Number of mature oocytes: number of MII oocytes. Other outcomes were not defined. |
Mahajan et al. (2016) [21] | Number of mature oocytes; total number of oocytes, 2PN zygotes; usable embryos | Number of mature oocytes; usable embryos | Ongoing pregnancy rate, clinical pregnancy rate, implantation rate, live birth rate | Usable embryos: embryos good for transfer and cryopreservation. Other outcomes were not defined. |
Ali et al. (2020) [13] | Number of mature oocytes; total number of oocytes; number of Grade 1 embryos; fertilization rate (without the exact fertilizaton number); implantation rate (without the exact sac number and transferred embryo number); clinical pregnancy rate; live birth rate | Number of mature oocytes | Ongoing pregnancy rate | Number of mature oocytes: number of MII oocytes; fertilization rate: the number of the fertilized oocytes divided by the total number of the retrieved oocytes per 100; implantation rate: total number of the sacs divided by the total number of the transferred embryos per 100; clinical pregnancy rate: the number of the cases with at least one sac in or out the uterus divided by the cycles initiated per 100; live birth rate: total number of the cases with at least one baby born after 24 weeks of gestation divided by the total number of the cycles initiated per 100. |
Schachter et al. (2008) [24] | Total number of oocytes; usable embryos; ongoing pregnancy rate; clinical pregnancy rate; implantation rate | Not mentioned | Number of mature oocytes; 2PN zygotes; live birth rate | Implantation rate: number of gestational sacs per embryo transferred. Other outcomes were not defined. |
Haas et al. (2019) [19] | Total number of oocytes; 2PN zygotes; ongoing pregnancy rate | Total number of oocytes, top-quality embryo | Number of mature oocytes, clinical pregnancy rate, implantation rate, live birth rate, usable embryos | Ongoing pregnancy: visualization of a gestational sac and fetal cardiac activity on transvaginal ultrasound. Other outcomes were not defined. |
Eftekhar et al. (2017) [20] | Number of mature oocytes; total number of oocytes, usable embryos; implantation number, clinical and ongoing pregnancy | Clinical pregnancy | 2PN zygotes, live birth rate | No definition of outcomes |
Kim et al. (2014) [22] | Number of mature oocytes; total number of oocytes, 2PN zygotes, top-quality embryo, clinical pregnancy, implantation rate, live birth rate, severe OHSS | Not mentioned | Ongoing pregnancy rate, usable embryos | Clinical pregnancy: increased serum β-hCG concentration. Other outcomes were not defined. |
Decleer et al. (2014) [23] | Number of mature oocytes; total number of oocytes, 2PN zygotes; Implantation rate; ongoing pregnancy rate | Number of mature oocytes | Clinical pregnancy rate, live birth rate, usable embryos | Number of mature oocytes: number of MII oocytes. Implantation rate: mean number of foetal sacs per embryo transferred. Ongoing pregnancy: confirmed by ultrasound 23 days after embryo transfer. Other outcomes were not defined. |