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Fig. 5 | Reproductive Biology and Endocrinology

Fig. 5

From: Fluorochloridone induces autophagy in TM4 Sertoli cells: involvement of ROS-mediated AKT-mTOR signaling pathway

Fig. 5

Effects of FLC treated in TM4 Sertoli cells autophagy activation. A, Flow cytometric analysis of MDC-labeled autophagic vesicles. B, Representative transmission electron micrographs depicting ultrastructure of TM4 Sertoli cells following 24 h treatment with FLC. Green arrowheads indicate the typical autophagosomes containing intracellular components and organelles; black arrowheads indicate the lysosomal. (a) control; (b) 40 μM FLC group; (c) 80 μM FLC group; (d) 160 μM FLC group. C, Western blot of autophagy-activating proteins (LC3, Beclin-1, P62). *P < 0.05 significantly different from the corresponding group

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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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