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Table 1 Baseline characteristics of patients

From: Impacts of Cyclosporin A on clinical pregnancy outcomes of patients with a history of unexplained transfer failure: a retrospective cohort study

Characteristic

CsA

(N = 58)

Con

(N = 120)

P value

Patients’ age at OPU (y)

32.0 (29.0-34.3)

31.5 (29.0–35.0)

0.698

Patients’ age during ET (y)

33.5 (30.0-35.3)

32.0 (30.0–36.0)

0.777

BMI (kg/m2)

22.5 ± 3.3

22.8 ± 3.5

0.596

Basal FSH (IU/mL)

5.9 (4.3–7.4)

6.0 (5.0–8.0)

0.225

No. of ET cycles

2.0 (2.0–3.0)*

2.0 (2.0–2.0)

0.027

No. of total embryos cryopreserved

6 (4–8)

5 (3–6)

0.138

No. of current cycle embryos transferred

2.0 (2.0–3.0)

2.0 (2.0–2.0)

0.230

No. of total prior embryos transferred

2.0 (2.0–2.0)*

2.0 (1.0–2.0)

0.006

Endometrium thickness(mm)

9.0 (8.0-10.3)

9.0 (8.0-10.5)

0.632

Causes of Infertility

  

> 0.05

 Female (%)

65.5 (38)

69.2 (83)

 

 Diminished ovarian reserve (%)

13.1 (5)

14.5 (12)

 

 Ovulation disease (%)

18.4 (7)

19.3 (16)

 

 Tubal disease (%)

63.2 (24)

60.2 (50)

 

 Unexplained (%)

5.3 (2)

6.0 (5)

 

 Male (%)

1.7 (1)

5.8 (7)

 

 Female and Male (%)

27.6 (16)

22.5 (27)

 

 Others (%)

5.2 (3)

2.5 (3)

 

 Primary (%)

48.3 (28)

55.0 (66)

 

 Secondary (%)

51.7 (30)

45.0 (54)

 

Development stage of ET embryos

  

> 0.05

 Day3 (%)

46.6 (27)

50.0 (60)

 

 Day5 (%)

15.5 (9)

14.2 (17)

 

 Day6 (%)

37.9 (22)

35.8 (43)

 

Endometrium morphology

  

> 0.05

 A (%)

58.6 (34)

58.3 (70)

 

 A- (%)

20.7 (12)

31.7 (38)

 

 Others (%)

20.7 (12)

10.0 (12)

 
  1. Values are shown as mean ± SD, median (IQR) or n (%). *P < 0.05 (P value*: Kruskal Wallis Rank Test for continuous variables) compared with the control group. CsA cyclosporin A; OPU oocyte pick-up; ET embryo transfer; BMI body mass index; FSH follicular stimulation hormone