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Table 3 Sensitivity, specificity, and overall diagnostic accuracy

From: Validation of preimplantation genetic tests for aneuploidy (PGT-A) with DNA from spent culture media (SCM): concordance assessment and implication

 

SCM

TE

Statistic

Value

95% CI

Value

Sensitivity

100%

92.60 to 100.00%

100%

Specificity

45.45%

16.75 to 76.62%

71.43%

Positive Predictive Value (PPV)

88.89%

82.35 to 93.21%

93.85%

Negative Predictive Value (NPV)

1000%

 

100.00%

Positive Likelihood Ratio (PLR)

1.83

1.07 to 3.14

3.50

Negative Likelihood Ratio (NLR)

0.00

 

0.00

Disease prevalence

81.36%

69.09 to 90.31%

81.33%

Overall diagnostic accuracy

89.83%

79.17 to 96.18%

94.67%