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Table 3 Sensitivity, specificity, and overall diagnostic accuracy

From: Validation of preimplantation genetic tests for aneuploidy (PGT-A) with DNA from spent culture media (SCM): concordance assessment and implication

  SCM TE
Statistic Value 95% CI Value
Sensitivity 100% 92.60 to 100.00% 100%
Specificity 45.45% 16.75 to 76.62% 71.43%
Positive Predictive Value (PPV) 88.89% 82.35 to 93.21% 93.85%
Negative Predictive Value (NPV) 1000%   100.00%
Positive Likelihood Ratio (PLR) 1.83 1.07 to 3.14 3.50
Negative Likelihood Ratio (NLR) 0.00   0.00
Disease prevalence 81.36% 69.09 to 90.31% 81.33%
Overall diagnostic accuracy 89.83% 79.17 to 96.18% 94.67%