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Fig. 1 | Reproductive Biology and Endocrinology

Fig. 1

From: HLA-A and HLA-DRB1 may play a unique role in ovarian teratoma-associated anti-N-methyl-D-aspartate receptor encephalitis

Fig. 1

The teratoma tissue proteome dataset from the iTRAQ quantitative proteomics analysis. a Protein mass distribution (X-axis: Molecular weight (kDa); Y-axis: Percentage of protein number). Peptide length distribution (X-axis: peptide length; Y-axis: corresponding peptide). Protein coverage distribution (X-axis: protein coverage range; Y-axis: corresponding protein number). b The volcano plot of the differentially expressed genes identified by iTRAQ analysis. The differentially expressed proteins, including 35 upregulated proteins and 1 downregulated protein, are illustrated in a volcano plot (|log2 fold change | ≥ 1.0 & P < 0.05). Each point (dot) represents the gene expression value; green (downregulated in the NMDAR-E group) and red (upregulated in the NMDAR-E group) dots represent significant DEPs. Black dots indicate nonsignificant proteins. c Cluster analysis of gene expression profiles. The color bar indicates the log2 fold change range between upregulation (red) and downregulation (blue)

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