Table 3 Comparison of outcomes at FPS stage of different trigger medicine at FPS stage
Characteristic | uhCG 10,000 IU | rhCG 250 μg | GnRha 0.2 mg | P value |
|---|---|---|---|---|
Number | 178 | 101 | 25 | Â |
AFC | 5.30 ± 4.19 | 5.57 ± 4.80 | 3.96 ± 2.52 | 0.248 |
FSH (IU/L) | 10.22 ± 5.51 | 9.88 ± 4.71 | 9.88 ± 3.12 | 0.841 |
Matemal age (years) | 38.30 ± 5.11 | 38.0 ± 4.92 | 38.04 ± 5.67 | 0.884 |
Total dose of gonadotrophin (IU) | 1524.27 ± 1298.85 | 1183.04 ± 813.58 | 906.00 ± 747.78 | 0.006 |
Duration of stimulation (days) | 6.42 ± 3.70 | 5.98 ± 3.16 | 4.24 ± 2.59 | 0.012 |
follicle of >10 mm on HCG day | 2.06 ± 1.44 | 2.18 ± 1.64 | 1.71 ± 0.62 | 0.367 |
No. of oocyte retrieved | 1.73 ± 1.30 | 1.72 ± 1.37 | 1.48 ± 0.96 | 0.66 |
No. of normal fertilized oocytes | 1.13 ± 0.87 | 1.03 ± 1.00 | 1.08 ± 0.78 | 0.669 |
No. of cleaved embryos | 1.08 ± 0.88 | 1.01 ± 1.00 | 1.00 ± 0.82 | 0.773 |
No. of cryopreserved embryos | 0.93 ± 0.80 | 0.87 ± 0.77 | 0.84 ± 0.62 | 0.745 |
No. of good embryos | 0.80 ± 0.78 | 0.76 ± 0.75 | 0.80 ± 0.65 | 0.929 |
Fertilization rates (%) | 63.64% | 58.62% | 70.27% | 0.327 |
Cleaved embryos rates (%) | 98.47% | 100% | 96.15% | 0.238 |
Rate of cryopreserved embryos (%) | 86.01% | 86.27% | 84.00% | 0.957 |
Rate of good embryos (%) | 73.58% | 75.49% | 80.00% | 0.766 |
the pregnancy rate per oocyte retrieval (%) | 8.03%(9/112) | 6.35%(4/63) | 6.67%(1/15) | 0.914 |
Pregnancy /FET (%) | 29.03%(9 /31) | 22.22%(4 /18) | 25.00%(1 / 4) | 0.871 |
Implantation rate (%) | 16.00%(12/75) | 13.79%(8 /58) | 8.33%(1 /12) | 0.768 |
Spontaneous abortion rate (%) | 44.44%(4 /9) | 50.00%(2/4) | 0.00%(0/1) | 0.656 |