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Table 1 The clinical, basal endocrine and metabolic characteristics of the study population

From: Growth hormone alleviates oxidative stress and improves the IVF outcomes of poor ovarian responders: a randomized controlled trial

 

POR-GH (n = 52)

POR-C (n = 53)

Non-POR (n = 58)

Age (years) ab

38.41 ± 2.91

38.20 ± 2.79

29.56 ± 3.12

Infertility duration (years)

4.57 ± 3.14

4.39 ± 3.22

3.47 ± 2.22

Risk factors for POR cycle (n) ab

20

18

0

Abnormal ORT cycle (n) ab

39

32

0

Previous POR cycle (n) ab

21

23

0

BMI (kg/m2)

22.09 ± 1.73

22.62 ± 2.73

22.19 ± 2.67

FSH (mIU/mL) ab

11.49 ± 2.94

10.97 ± 2.75

5.89 ± 1.76

LH (mIU/mL)

4.59 ± 1.83

4.36 ± 1.57

4.29 ± 1.45

FSH / LH ratio ab

2.74 ± 1.57

2.53 ± 1.68

1.38 ± 0.75

E2 (pg/mL) ab

75.98 ± 34.05

72.34 ± 26.87

40.62 ± 11.19

P (ng/mL)

0.64 ± 0.39

0.54 ± 0.35

0.55 ± 0.20

TT (ng/mL)

0.37 ± 0.19

0.41 ± 0.20

0.43 ± 0.15

AMH (ng/mL) ab

0.88 ± 0.67

0.81 ± 0.41

3.50 ± 1.91

PRL (μIU/mL)

162.59 ± 50.19

171.25 ± 52.32

163.51 ± 45.79

HOMA-IR

1.68 ± 1.25

1.71 ± 1.34

1.67 ± 1.33

AFC ab

4.12 ± 1.71

4.06 ± 2.11

15.30 ± 4.56

  1. Note: Data are presented as the mean ± SD or number. BMI body mass index, FSH follicle-stimulating hormone, LH luteinizing hormone, E2 oestradiol, P progesterone, TT total testosterone, AMH anti-Mullerian hormone, PRL prolactin, HOMA-IR homeostatic model assessment of insulin resistance, AFC antral follicle count
  2. a P < 0.05 the POR-GH group versus the non-POR group
  3. b P < 0.05 the POR-C group versus the non-POR group