Fig. 2
From: Histone acetylation and the role of histone deacetylases in normal cyclic endometrium
Global histone acetylation changes throughout the menstrual cycle. Global histone acetylation changes have been observed in human endometrium during different stages of menstrual cycle. Acetylation levels of H2AK5, H3K9, and H4K8 are elevated during early proliferative phase, the acetylation levels decline subsequently until ovulation then a significant increase in acetylation levels of H4K8 is observed in early secretory phase which reaches its peak during mid secretory phase. A significant decline is observed in global histone acetylation levels in H2AK5, H3K9, and H4K8 during late secretory phase [6]. (Created with BioRender.com)