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Table 3 Single-factor analysis of factors related to FET outcomes

From: Gonadotropin-releasing hormone agonist combined with hormone replacement therapy does not improve the reproductive outcomes of frozen-thawed embryo transfer cycle in elderly patients: a retrospective study

Clinical indicators

Clinical pregnancy rate

Sustained pregnancy rate

Value

OR value(95% CI)

P value

OR value(95% CI)

P value

Age (y)

0.8(0.753–0.849)

< 0.001***

0.725(0.673–0.781)

< 0.001***

FSH

0.96(0.933–0.988)

0.005**

0.949(0.915–0.984)

0.005**

AFC

1.050(1.029–1.071)

< 0.001***

1.065(1.042–1.089)

< 0.001***

Intimal thickness

1.030(0.974–1.090)

0.301

1.055(0.991–1.124)

0.093

BMI

1.040(1.000–1.081)

0.049

1.036(0.991–1.082)

0.117

No of embryos transferred

1

Ref.

 

Ref.

 

2

1.494(1.132–1.972)

0.005**

1.238(0.908–1.688)

0.177

3

1.927(1.141–3.254)

0.014*

1.153(0.629–2.116)

0.645

Embryos transferred

Cleavage stage

Ref.

 

Ref.

 

Blastocyst

1.786(1.413–2.258)

< 0.001***

1.69(1.301–2.195)

< 0.001***

FET strategy

GnRHa-HRT

Ref.

 

Ref.

 

HRT

1.169(0.880–1.553)

0.282

1.392(0.996–1.946)

0.053

Clinical indicators

Live birth rate

Abortion rate

Value

OR value(95% CI)

P value

OR value(95% CI)

P value

Age (y)

0.721(0.668–0.778)

< 0.001***

1.31(1.179–1.454)

< 0.001***

FSH

0.948(0.913–0.984)

0.005**

1.032(0.987–1.080)

0.166

AFC

1.065(1.042–1.089)

< 0.001***

0.953(0.921–0.986)

0.006**

Intimal thickness

1.048(0.983–1.118)

0.149

0.979(0.891–1.076)

0.748

BMI

1.030(0.985–1.076)

0.196

0.989(0.924–1.058)

0.658

No of embryos transferred

1

Ref.

 

Ref.

 

2

1.194(0.872–1.635)

0.269

1.382(0.838–2.279)

0.205

3

1.108(0.597–2.057)

0.746

2.157(0.944–4.927)

0.068

Embryos transferred

Cleavage stage

Ref.

 

Ref.

 

Blastocyst

1.621(1.242–2.115)

< 0.001***

1.043(0.711–1.529)

0.829

FET strategy

GnRHa-HRT

Ref.

 

Ref.

 

HRT

1.492(1.055–2.111)

0.024*

0.588(0.368–0.939)

0.026*

  1. *P < 0.05, **P < 0.01, ***P < 0.001 for Chi-square test
  2. Abbreviations: OR odds ratio; CI 95% confidence interval; FSH follicle-stimulating hormone; AFC antral follicle count; BMI body mass index; FET frozen-thawed embryo transfer