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Table 3 Single-factor analysis of factors related to FET outcomes

From: Gonadotropin-releasing hormone agonist combined with hormone replacement therapy does not improve the reproductive outcomes of frozen-thawed embryo transfer cycle in elderly patients: a retrospective study

Clinical indicators Clinical pregnancy rate Sustained pregnancy rate
Value OR value(95% CI) P value OR value(95% CI) P value
Age (y) 0.8(0.753–0.849) < 0.001*** 0.725(0.673–0.781) < 0.001***
FSH 0.96(0.933–0.988) 0.005** 0.949(0.915–0.984) 0.005**
AFC 1.050(1.029–1.071) < 0.001*** 1.065(1.042–1.089) < 0.001***
Intimal thickness 1.030(0.974–1.090) 0.301 1.055(0.991–1.124) 0.093
BMI 1.040(1.000–1.081) 0.049 1.036(0.991–1.082) 0.117
No of embryos transferred 1 Ref.   Ref.  
2 1.494(1.132–1.972) 0.005** 1.238(0.908–1.688) 0.177
3 1.927(1.141–3.254) 0.014* 1.153(0.629–2.116) 0.645
Embryos transferred Cleavage stage Ref.   Ref.  
Blastocyst 1.786(1.413–2.258) < 0.001*** 1.69(1.301–2.195) < 0.001***
FET strategy GnRHa-HRT Ref.   Ref.  
HRT 1.169(0.880–1.553) 0.282 1.392(0.996–1.946) 0.053
Clinical indicators Live birth rate Abortion rate
Value OR value(95% CI) P value OR value(95% CI) P value
Age (y) 0.721(0.668–0.778) < 0.001*** 1.31(1.179–1.454) < 0.001***
FSH 0.948(0.913–0.984) 0.005** 1.032(0.987–1.080) 0.166
AFC 1.065(1.042–1.089) < 0.001*** 0.953(0.921–0.986) 0.006**
Intimal thickness 1.048(0.983–1.118) 0.149 0.979(0.891–1.076) 0.748
BMI 1.030(0.985–1.076) 0.196 0.989(0.924–1.058) 0.658
No of embryos transferred 1 Ref.   Ref.  
2 1.194(0.872–1.635) 0.269 1.382(0.838–2.279) 0.205
3 1.108(0.597–2.057) 0.746 2.157(0.944–4.927) 0.068
Embryos transferred Cleavage stage Ref.   Ref.  
Blastocyst 1.621(1.242–2.115) < 0.001*** 1.043(0.711–1.529) 0.829
FET strategy GnRHa-HRT Ref.   Ref.  
HRT 1.492(1.055–2.111) 0.024* 0.588(0.368–0.939) 0.026*
  1. *P < 0.05, **P < 0.01, ***P < 0.001 for Chi-square test
  2. Abbreviations: OR odds ratio; CI 95% confidence interval; FSH follicle-stimulating hormone; AFC antral follicle count; BMI body mass index; FET frozen-thawed embryo transfer