Fig. 2From: Downregulation of hsa_circ_0005243 induces trophoblast cell dysfunction and inflammation via the β-catenin and NF-κB pathwaysDownregulation of hsa_circ_0005243 suppresses trophoblast cell proliferation and promotes apoptosis. a hsa_circ_0005243 expression was determined after transfection with siRNAs. b CCK8 analysis revealed a significant reduction in cell viability following hsa_circ_0005243 knockdown. c, d EdU (c) and colony formation (d) assays showed that depletion of hsa_circ_0005243 inhibited cell proliferation. e Flow cytometry revealed an increase in apoptosis following hsa_circ_0005243 knockdown. Data are presented as the mean ± SD, **p < 0.01Back to article page