Table 1 Comparison of oocyte cryopreservation and ovarian tissue cryopreservation

Oocyte Cryopreservation

1) Well-established

2) Cost-efficiently and easily-approached

3) No need for surgery

1) Only for reproductively mature carriers

2) Time-consuming

3) Cannot restore endocrine function

Reproductively mature carriers with abundant time

Ovarian Tissue Cryopreservation

1) Restoration of endocrine function

2) Available for pre-puberty carriers

3) Menstrual cycle independent and no need for delay in oncologic treatment

1) Experimental and available only in highly specialized centers

2) Success highly dependent on ovarian reserve

3) Risk of ovarian cancer

Pre-puberty carriers; carriers with adjunct therapy planned or already in therapy