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Table 1 Comparison of oocyte cryopreservation and ovarian tissue cryopreservation

From: Fertility preservation in BRCA mutation carriers—efficacy and safety issues: a review

 AdvantagesDisadvantagesRecommended applications
Oocyte Cryopreservation1) Well-established
2) Cost-efficiently and easily-approached
3) No need for surgery
1) Only for reproductively mature carriers
2) Time-consuming
3) Cannot restore endocrine function
Reproductively mature carriers with abundant time
Ovarian Tissue Cryopreservation1) Restoration of endocrine function
2) Available for pre-puberty carriers
3) Menstrual cycle independent and no need for delay in oncologic treatment
1) Experimental and available only in highly specialized centers
2) Success highly dependent on ovarian reserve
3) Risk of ovarian cancer
Pre-puberty carriers; carriers with adjunct therapy planned or already in therapy