Fig. 4

Significant and non-significant expression differences of Wnt components in mouse oocytes and in 2-cell- and blastocyst-stage embryos between the miR-451 inhibitor-injected and control groups. The histograms present five genes that are within or regulate the Wnt signalling pathway with markedly different expression levels (a) and seven genes that are within or regulate the Wnt signalling pathway with non-significant differences in expression level (b) between the miR-451 inhibitor (n = 160) and control (n = 95) groups. All experiments were repeated at least thrice. Unpaired t-test; *P < 0.05; **P < 0.01; ***P < 0.001