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Table 2 Relationship of the cf-nDNA and the relative cf-mtDNA (cf-ND1/cf-β-globin ratio) levels in human follicular fluid with embryo development outcomes

From: Cell-free mitochondrial DNA in human follicular fluid: a promising bio-marker of blastocyst developmental potential in women undergoing assisted reproductive technology

FF associated with n of FF(%) cf-nDNA (ng/ml) relative cf-mtDNA
MD (IQR) OR (95% CI) p MD (IQR) OR (95% CI) p
High-quality embryos 89 (62.68) 0.23 (0.13–0.50) 0.94 (0.78, 1.12) 0.46 5.27 (2.99–9.67) 1.00 (0.95, 1.05) 0.94
poor-quality embryos 53 (37.32) 0.24 (0.13–0.32) 7.39 (4.14–10.07)
blastocysts 22 (51.16) 0.63 (0.21–1.81) 26.43 (0.75, 929.72) 0.071 2.84 (1.53–6.99) 0.87 (0.76, 0.99) 0.030
No blastocysts 21 (48.84) 0.14 (0.08–0.25) 7.80 (4.66–10.34)
  1. Percentages are calculated within groups. Data are presented as MD (IQR) and are analyzed using multivariate logistic regression. Statistical significance was assumed at P < 0.05. FF follicular fluid, MI metaphase I, MII metaphase II, GV germinal vesicle, OR odds ratio, CI confidence interval, MD Median, IQR interquartile range