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Fig. 4 | Reproductive Biology and Endocrinology

Fig. 4

From: Expression of the plasminogen system in the physiological mouse ovary and in the pathological polycystic ovary syndrome (PCOS) state

Fig. 4

Expression of plasminogen/plasmin (NBP2–19859) or plasminogen alone (NB300–544) in normal and PCOS mouse ovaries. Left: Top: (a) plasminogen/plasmin (NBP2–19859) and Bottom: (b) plasminogen alone (NB300–544). Representative histological images are from normal (control) (Ai, Aiii, Bi, Biii) or PCOS ovaries (Aii, Aiv, Bii, Biv) stained with an (a) anti-plasminogen/plasmin or (b) an anti-plasminogen only antibody. The scale bar represents 500 μm for Ai, Aii, Bi & Bii and 100 μm for Aiii, Aiv, Biii & Biv. Right: Top: Negative control for plasminogen/plasmin on mouse liver; Middle: Graphical representation comparing the percentage of ovarian staining (Area Fraction ROI) for plasminogen/plasmin and plasminogen alone between normal and PCOS ovaries for 6 replicates of each experimental group (mean ± SD) and Bottom: Negative control for plasminogen alone on mouse liver

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