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Table 2 Comparison of semen parameters before and after treatment with NAC. Sperm parameters significantly improved after treatment with NAC compared to before treatment

From: Effects of N-acetyl-cysteine supplementation on sperm quality, chromatin integrity and level of oxidative stress in infertile men

Sperm Parameters

Before NAC (n = 50)

After NAC (n = 50)

P- Value

Volume (ml)

3.58 ± 0.12

4.02 ± 0.18*

P = 0.01

Total Motility (%)

31.42 ± 0.60

35.18 ± 1.21*

P = 0.01

Progressive motility (a + b) (%)

20.60 ± 0.77

24.54 ± 1.08*

P = 0.001

Non-Progressive motility (%)

19.10 ± 0.76

16.00 ± 1.19*

P = 0.01

Immotile Sperm (%)

63.00 ± 0.71

61.82 ± 0.79*

P = 0.01

Sperm concentration (106/mL)

46.52 ± 1.80

51.06 ± 2.51*

P = 0.02

Abnormal Morphology (%)

98.12 ± 0.11

96.02 ± 0. 16*

P = 0.001

  1. NAC: N-acetyl-cysteine. Significant differences in bold