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Table 4 Analyses of factors affecting retrieved oocytes > 3 in poor ovarian responders with DHEA supplementation

From: Dehydroepiandrosterone (DHEA) supplementation improves in vitro fertilization outcomes of poor ovarian responders, especially in women with low serum concentration of DHEA-S: a retrospective cohort study

 

Univariate analysis

Multivariate analysis

OR (95% CI)

p value

Adjusted OR (95% CI)

p value

DHEA-S, μg/dl

  < 180 vs. ≥ 180

6.62(1.90–22.73)

0.003

5.92(1.48–23.26)

0.012

Age, years

0.94(0.80–1.09)

0.404

  

BMI, kg/m2

1.00(0.84–1.20)

0.986

  

Infertility duration

1.03(0.92–1.16)

0.620

  

Previous IVF attempts, n

1.07(0.86–1.34)

0.541

  

Types of infertility

 Primary vs. Secondary

1.81(0.65–5.02)

0.258

  

aBologna criteria category

 (1 + 3) vs. (1 + 2)

0.09(0.01–1.00)

0.050

0.22(0.02–2.92)

0.253

 (2 + 3) vs. (1 + 2)

0.18(0.02–1.92)

0.154

0.43(0.03–6.05)

0.530

 (1 + 2 + 3) vs. (1 + 2)

0.09(0.01–0.97)

0.047

0.17(0.01–2.05)

0.164

  1. DHEA dehydroepiandrosterone, OR odd ratio, CI confidence interval, DHEA-S dehydroepiandrosterone-sulfate, BMI body mass index, IVF in vitro fertilization
  2. aPoor ovarian responders (PORs) meet the Bologna criteria, having at least two of the three following features: (1) advanced maternal age (≥ 40 years) or any other risk factor for POR; (2) a previous POR (≤ 3 oocytes with a conventional stimulation protocol); (3) an abnormal ovarian reserve test. Abnormal ovarian reserve test was defined as antral follicle count (AFC) < 5 or anti-Müllerian hormone (AMH) < 1 ng/mL in this study
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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