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Table 4 Analyses of factors affecting retrieved oocytes > 3 in poor ovarian responders with DHEA supplementation

From: Dehydroepiandrosterone (DHEA) supplementation improves in vitro fertilization outcomes of poor ovarian responders, especially in women with low serum concentration of DHEA-S: a retrospective cohort study

  Univariate analysis Multivariate analysis
OR (95% CI) p value Adjusted OR (95% CI) p value
DHEA-S, μg/dl
  < 180 vs. ≥ 180 6.62(1.90–22.73) 0.003 5.92(1.48–23.26) 0.012
Age, years 0.94(0.80–1.09) 0.404   
BMI, kg/m2 1.00(0.84–1.20) 0.986   
Infertility duration 1.03(0.92–1.16) 0.620   
Previous IVF attempts, n 1.07(0.86–1.34) 0.541   
Types of infertility
 Primary vs. Secondary 1.81(0.65–5.02) 0.258   
aBologna criteria category
 (1 + 3) vs. (1 + 2) 0.09(0.01–1.00) 0.050 0.22(0.02–2.92) 0.253
 (2 + 3) vs. (1 + 2) 0.18(0.02–1.92) 0.154 0.43(0.03–6.05) 0.530
 (1 + 2 + 3) vs. (1 + 2) 0.09(0.01–0.97) 0.047 0.17(0.01–2.05) 0.164
  1. DHEA dehydroepiandrosterone, OR odd ratio, CI confidence interval, DHEA-S dehydroepiandrosterone-sulfate, BMI body mass index, IVF in vitro fertilization
  2. aPoor ovarian responders (PORs) meet the Bologna criteria, having at least two of the three following features: (1) advanced maternal age (≥ 40 years) or any other risk factor for POR; (2) a previous POR (≤ 3 oocytes with a conventional stimulation protocol); (3) an abnormal ovarian reserve test. Abnormal ovarian reserve test was defined as antral follicle count (AFC) < 5 or anti-Müllerian hormone (AMH) < 1 ng/mL in this study