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Table 1 Basic characteristics of poor ovarian responders with or without DHEA

From: Dehydroepiandrosterone (DHEA) supplementation improves in vitro fertilization outcomes of poor ovarian responders, especially in women with low serum concentration of DHEA-S: a retrospective cohort study

Parameters POR (n = 84) POR with DHEA (n = 67) p value
Age (years) 39.8 ± 3.7 39.1 ± 3.3 0.208
Body mass index (kg/m2) 21.8 ± 3.8 21.9 ± 2.9 0.857
Infertility duration (year) 5.3 ± 4.5 5.6 ± 4.2 0.712
Previous IVF attempts(n) 2.3 ± 2.2 2.6 ± 2.2 0.480
Types of infertility n (%) 0.548
 Primary infertility 41/84 (48.8%) 36/67 (53.7%)  
 Secondary infertility 43/84 (51.2%) 31/67 (46.3%)  
Basal FSH (IU/l) 6.3 ± 4.6 7.1 ± 4.2 0.305
DHEA-S (μg/dl) 212.9 ± 85.9 199.2 ± 65.0 0.316
Antral follicle counts (n) 3.3 ± 1.4 3.3 ± 1.3 0.921
Anti-Müllerian hormone(ng/ml) 0.7 ± 0.4 0.7 ± 0.5 0.932
aBologna criteria category n (%) 0.170
 1 + 2 16/84 (19.0%) 5/67 (7.5%)  
 1 + 3 16/84 (19.0%) 19/67 (28.4%)  
 2 + 3 21/84 (25.0%) 17/67 (25.4%)  
 1 + 2 + 3 31/84 (36.9%) 26/67 (38.8%)  
  1. Data are presented as mean ± standard deviation and n (%)
  2. POR poor ovarian responder, DHEA dehydroepiandrosterone, IVF in vitro fertilization, FSH follicle stimulation hormone, DHEA-S dehydroepiandrosterone-sulfate
  3. aPORs meet the Bologna criteria, having at least two of the three following features: (1) advanced maternal age (≥ 40 years) or any other risk factor for POR; (2) a previous POR (≤ 3 oocytes with a conventional stimulation protocol); (3) an abnormal ovarian reserve test. Abnormal ovarian reserve test was defined as antral follicle count (AFC) < 5 or anti-Müllerian hormone (AMH) < 1 ng/mL in this study