Acrosome reaction and chromatin integrity as additional parameters of semen analysis to predict fertilization and blastocyst rates

Table 4 Logit model for a successful fertilization

Fertilization ≥60%	Beta coefficient (CI)^a	SE	p value
% ARIC	0.24 (0.10–0.37)	0.06	0.000
% Morphology	0.59 (0.14–1.04)	0.23	0.01
Constant	−4.58 (−7.17 to −1.98)	1.32	0.001

ARIC = Acrosome response to an ionophore challenge, ^a95% confidence interval. ROC cutoff = 0.65. AUC = 803. Sensitivity = 63.2%. Specificity = 80.6%. Positive predictive value = 80%. Negative predictive value = 64.1%. n = 69. Constant = βo from the logit model (Ln(basal probability of Fertilization ≥60% if ARIC and % morphology are equal to zero))

ISSN: 1477-7827