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Table 3 Bivariate associations between sperm parameters and IVF outcomes

From: Acrosome reaction and chromatin integrity as additional parameters of semen analysis to predict fertilization and blastocyst rates

Variable Beta coefficient /R2
Fertilization (%)
(CI 95% β)a
Viable embryos (%)
(CI 95% β)a
WHO parameters
 Volume (ml) 0.86 / 0.003
(− 3.09, 4.81)
−2.55 / 0.010
(− 8.67, 3.56)
 Concentration (× 106/ml) − 0.02 / 0.000
(− 0.10, 0.11)
0.09 / 0.020
(− 0.07, 0.26)
 Total count (× 106) 0.00 / 0.003
(− 0.02, 0.03)
− 0.04 / 0.000
(− 0.03, 0.04)
 Motility (%) 3.19 / 0.000
(− 0.31, 0.37)
− 0.13 / 0.003
(− 0.66, 0.40)
 Morphology (%) 3.56 / 0.054
(0.05, 7.18) *
−2.75 / 0.013
(− 8.48, 2.98)
 Viability (%) 0.20 / 0.012
(− 0.24, 0.66)
− 0.20 / 0.004
(− 0.90, 0.50)
 pH − 0.92 / 0.000
(− 9.29,7.44)
−5.79 / 0.011
(− 18.71, 7.12)
 Leukocytes (× 106/ml) − 3.93 / 0.015
(− 11.66, 3.80)
−9.35 / 0.035
(− 21.23, 2.52)
Sperm quality and function parameters (%)
 sAR −5.92 / 0.276
(− 8.26, − 3.58) ***
− 4.19 / 0.057
(− 8.33, − 0.04) *
 iAR 1.83 / 0.150
(0.76, 2.89) ***
−0.87 / 0.014
(− 0.90, 2.65)
 ARIC 2.10 / 0.270
(1.26, 2.94) ***
−0.18 / 0.035
(− 0.32, 2.68)
 DFI 0.18 / 0.003
(− 0.59, 0.96)
−1.77 / 0.127
(− 2.91, − 0.64) **
 HDS −0.65 / 0.013
(− 2.02, 0.72)
−0.52 / 0.003
(− 2.66, 1.61)
  1. sAR = Spontaneous acrosome reaction, iAR = Induced acrosome reaction, ARIC = Acrosome response to an ionophore challenge, DFI = DNA fragmentation index, HDS = High DNA Stainability. aCI= 95% confidence interval. In bold, the values with statistical significance are highlighted. *p = 0.05, **p = 0.003, ***p < 0.0001. n = 69