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Table 1 Mmp9 crosses performed in experiments

From: PAPP-A2 deficiency does not exacerbate the phenotype of a mouse model of intrauterine growth restriction

Mating type Female MMP9 genotype Male MMP9 genotype
0 −/− −/−
1 −/− +/−
2 +/− −/−
3 +/− +/−
4 +/+ +/+
  1. Each type of Mmp9 cross included either no functional Pappa2 alleles (Pappa2−/− x Pappa2−/−) or at least one functional Pappa2 (achieved with various combinations of female and male genotype)