Table 1 Gene ontology of genes affected by heat in both spermatocytes and spermatids
From: The thermo-sensitive gene expression signatures of spermatogenesis
Nō. of genes | Name of genes | |
|---|---|---|
Molecular functions | ||
Binding (GO:0005488) | 21 | Taf9, Cast, Apbb1, Crip1, Zfp202, Timp1, Lilrb3l, AC120291 (Mbd3), Sptbn1, Cast, Sept4, AC120291 (Mex3d), Prpf8, Rabgap1l, Gtf2b, Tdrd5, Micu1, Upf1, Prelp, Micu2, Camk2d |
Catalytic activity (GO:0003824) | 26 | Cst, Clk3, Hsd11b1, Mink1, Timp1, Abcc12, AC120291 (Atp8b3), Scpep1, Cast, Sept4, Grip1, AC120291 (Mex3d), Acly, Serpinf1, Prpf8, Ptpru, Rabgap1l, Tdrd5, Txnrd1, Upf1, Nt5c3b, ldhc, Mipep, Scamp1, LOC316124, Camk2d |
Receptor activity (GO:0004872) | 2 | Lilrb3l, Ptpru |
Signal transducer activity (GO:0004871) | 1 | Mink1 |
Structural molecule activity (GO:0005198) | 7 | Emp1, Crip1, Mgp, C1qa, Sptbn1, Sept4, Mrps14 |
Transporter activity (GO:0005215) | 6 | Abcc12, AC120291 (Atp8b3), Mct4, LOC316124, Mct2,Mct1 |
Biological process | ||
Biological adhesion (GO:0022610) | 7 | Cfb, Col6a2, Ccdc80, C1qa, Cfb, Rabgap1l, Prelp |
Biological regulation (GO:0065007) | 6 | Crip1, Mink1, Timp1, AC120291 (Atp8b3), AC120291 (Mbd3), Serpinf1 |
Cellular component organization or biogenesis (GO:0071840) | 8 | Col6a2, Crip1, Mink1, AC120291 (Atp8b3), C1qa, AC120291 (Mbd3) |
Cellular process (GO:0009987) | 29 | Emp1, Cfb, Col6a2, Apbb1, Ccdc80, AC120291 (Plk5), Zfp202, Mink1, Timp1, AC120291 (Atp8b3), C1qa, Lilrb3l, AC120291 (Mbd3), Wdr36, Scpep1, Sptbn1, Cfb, Sept4, Grip1, Prpf8, Rabgap1l, Prkar2b, Upf1, Prelp, Mipep, Mct4, Mrps14, Mct2, Camk2d |
Developmental process (GO:0032502) | 6 | Crip1, Mink1, C1qa, Sptbn1, Prelp, Camk2d |
Immune system process (GO:0002376) | 9 | Cfb, Col6a2, Crip1, Ccdc80, Abcc12, C1qa, Col3a1, Cfb, LOC316124 |
Localization (GO:0051179) | 9 | Abcc12, AC120291, Cast, Rabgap1l, Scamp1, Mct4, LOC316124, Mct2, Mct1 |
Metabolic process (GO:0008152) | 26 | Taf9, Cast, Apbb1, Crip1, Zfp202, Hsd11b1, Mink1, Timp1, AC120291 (Atp8b3), AC120291 (Mbd3), Wdr36, Scpep1, AC120291 (Mex3d), Acly, Prpf8, Ptpru, Sdhaf3, Gtf2b, Tdrd5, Txnrd1, Upf1, ldhc, Prelp, Mipep, LOC316124, Mrps14 |
Multicellular organismal process (GO:0032501) | 4 | Mink1, Col3a1, Grip1, Prelp |
Reproduction (GO:0000003) | 1 | Crip1 |
Response to stimulus (GO:0050896) | 8 | Taf9, Cfb, Lilrb3, Crip1, Mink1, Timp1, Abcc12, Cfb |
Cellular Component | ||
Cell junction (GO:0030054) | 1 | Grip1 |
Cell part (GO:0044464) | 15 | Emp1, Apbb1, Crip1, Zfp202, Mink1, AC120291 (Atp8b3), AC120291 (Mbd3), Wdr36, Sptbn1, Sept4, Prpf8, Ptpru, Mipep, Mrps14, Camk2d |
Extracellular matrix (GO:0031012) | 4 | Col6a2, Timp1, C1qa, Prelp |
Extracellular region (GO:0005576) | 4 | Timp1, C1qa, Serpinf1, Prelp |
Macromolecular complex (GO:0032991) | 3 | Wdr36, Prpf8, Mrps14 |
Membrane (GO:0016020) | 4 | AC120291 (Atp8b3), Grip1, Mct4, Mct1 |
Organelle (GO:0043226) | 9 | Apbb1, Zfp202, AC120291 (Atp8b3), AC120291 (Mbd3), AC120291, Sept4, Prpf8, Prelp, Mipep |
Protein class | ||
Calcium-binding protein (PC00060) | 3 | Mgp, Micu1, Micu2 |
Cell adhesion molecule (PC00069) | 1 | C1qa |
Cell junction protein (PC00070) | 1 | Grip1 |
Cytoskeletal protein (PC00085) | 5 | Emp1, Crip1, Ivns1abp, Sptbn1, Sept4 |
Defense/immunity protein (PC00090) | 1 | Lilrb3l |
Enzyme modulator (PC00095) | 5 | Cast, Cast (Erc2), Sept4, Serpinf1, Rabgap1l |
Extracellular matrix protein (PC00102) | 3 | Mgp, C1qa, Prelp |
Hydrolase (PC00121) | 8 | Ivns1abp, AC120291 (Atp8b3), Scpep1, Ptpru, Rabgap1l, Upf1, Nt5c3b, Mipep |
Ligase (PC00142) | 3 | AC120291 (Mex3d), Acly, LOC316124 |
lyase (PC00144) | 1 | Acly |
Membrane traffic protein (PC00150) | 1 | Cast |
Nucleic acid binding (PC00171) | 9 | Taf9, Crip1, AC120291 (Mbd3), Wdr36, AC120291 (Mex3d), Prpf8, Tdrd5, Upf1, Mrps14 |
Oxidoreductase (PC00176) | 3 | Hsd11b1, Txnrd1, ldhc |
Signaling molecule (PC00207) | 3 | Apbb1, Mgp, Lilrb3l |
Structural protein (PC00211) | 1 | Mgp |
Transcription factor (PC00218) | 4 | Taf9, Crip1, Ivns1abp, Gtf2b |
Transferase (PC00220) | 5 | Clk3, Grip1, Acly, Scamp1, Camk2d |
Transporter (PC00227) | 5 | Abcc12, AC120291 (Atp8b3), Mct4, Mct2, Mct1 |
Transfer carrier protein | 1 | Scamp1 |
Receptors | 2 | Ptpru, Prelp |
Pathways | ||
Alzheimer disease-amyloid secretase pathway (P00003) | 1 | Apbb1 |
Alzheimer disease-presenilin pathway (P00004) | 1 | Apbb1 |
Angiogenesis (P00005) | 1 | AC120291 (Apc2) |
Cytoskeletal regulation by Rho GTPase (P00016) | 2 | Arpc2, Gtf2b |
General transcription regulation (P00023) | 2 | Taf9, Gtf2b |
Inflammation mediated by chemokine and cytokine signaling pathway (P00031) | 3 | Col6a2, Arpc2, camk2d |
Integrin signalling pathway (P00034) | 3 | Col6a2, Arpc2, Col3a1 |
Parkinson disease (P00049) | 1 | Sept4 |
Pyruvate metabolism (P02772) | 1 | Acly |
Transcription regulation by bZIP transcription factor (P00055) | 3 | Taf9, Gtf2b, Prkar2b |
Wnt signaling pathway (P00057) | 1 | AC120291 (Apc2) |
5HT receptor Mediated signaling | 1 | Prkar2b |
Apoptosis signalling pathway | 1 | daxx |
b 1 adrenergic signaaling | 1 | Prkar2b |
b2 adrenegenic signalling | 1 | Prkar2b |
dopamine receptor mediated signaling | 1 | Prkar2b |
fas signalling pathway | 1 | daxx |
endothilin signalling pathway | 1 | Prkar2b |
muscarinie acetylcholine receptor 2 and 4 signalling | 1 | Prkar2b |
metabotropic glutamate receptor III pathway | 1 | Prkar2b |
metabotropic glutamate receptor II pathway | 1 | Prkar2b |
ionotropic glutamate receptor pathway | 1 | Camk2d |
GABA b receptor signaling | 1 | Prkar2b |