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Table 2 Serum hormone profile after 21 days of letrozole treatment

From: GnRH dysregulation in polycystic ovarian syndrome (PCOS) is a manifestation of an altered neurotransmitter profile

 

Estradiol (pg/ml)

Testosterone (ng/ml)

Progesterone (ng/ml)

Insulin(μIU/ml)

HOMA-IR

Control

132.3 ± 17.37

0.315 ± 0.05

12.25 ± 0.54

7.42 ± 1.04

1.56 ± 0.14

Let-treated

139.3 ± 19.10

1.177 ± 0.07***

9.95 ± 0.39*

15.54 ± 1.27***

4.40 ± 0.21***

  1. All values are presented as Mean ± SEM; n = 6 per group; *P < 0.05; ***P < 0.001 as compared to control
  2. \( \mathrm{HOMA}\kern0.5em \hbox{-} \kern0.5em \mathrm{IR}\kern0.5em =\kern0.5em \frac{\left[\mathrm{Glucose}\kern0.5em \left(\mathrm{mg}/\mathrm{dl}\right)\kern0.5em \times \kern0.5em \mathrm{Insulin}\kern0.5em \left(\upmu \mathrm{IU}/\mathrm{ml}\right)\right]\kern0.5em }{405} \)
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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