Table 4 Gestational diabetes mellitus (GDM) patients´ characteristics and laboratory parameters in the mid-trimester cohort study
From: Is Afamin a novel biomarker for gestational diabetes mellitus? A pilot study
Parameter | Gestational diabetes mellitus treated with dietary intervention (dGDM) n = 17 | Gestational diabetes mellitus treated with insulin (iGDM) n = 12 | p-value |
|---|---|---|---|
Gestational age at 75 g-oral glucose-tolerance-test (OGTT) performance (days) | |||
Mean (± standard deviation, SD) | 174 (32) | 158 (55) | 0.32 |
Median (Interquartile range, IQR) | 183 (157–200) | 167 (120–199) | |
Maternal age (years) | |||
Mean (± SD) | 34.59 (4.64) | 35.58 (5.85) | 0.40 |
Median (IQR) | 36 (32.25–38.00) | 37.50 (30.00–39.50) | |
Body-mass-index (kg/m2) | |||
Mean (± SD) | 28.05 (5.28) | 35.53 (10.49) | 0.02 |
Median (IQR) | 26.60 (24.55–31.33) | 30.50 (29.70–38.90) | |
Fasting Insulin (μlU/ml) | |||
Mean (± SD) | 9.95 (5.04) | 16.53 (9.79) | 0.06 |
Median (IQR) | 9.90 (5.48–14.30) | 13.40 (9.35–20.35) | |
1 h Insulin (μlU/ml) | |||
Mean (± SD) | 82.04 (24.47) | 150.69 (68.15) | 0.003 |
Median (IQR) | 75.50 (63.98–103.25) | 125.00 (111.50–213.00) | |
2 h Insulin (μlU/ml) | |||
Mean (± SD) | 101.59 (40.58) | 148.88 (60.45) | 0.02 |
Median (IQR) | 102.00 (71.80–123.50) | 141.00 (107.50–187.50) | |
Fasting glucose (mg/dl) | |||
Mean (± SD) | 79.47 (9.27) | 89.92 (12.93) | 0.02 |
Median (IQR) | 77.00 (73.00–89.25) | 93.50 (82.00–98.00) | |
1 h glucose (mg/dl) | |||
Mean (± SD) | 171.53 (16.90) | 189.58 (33.07) | 0.14 |
Median (IQR) | 171.00 (160.25–187.50) | 183.50 (171.50–202.50) | |
2 h glucose (mg/dl) | |||
Mean (± SD) | 155.35 (20.34) | 148.92 (33.08) | 0.81 |
Median (IQR) | 155.00 (151.25–172.00) | 157.00 (135.00–169.00) | |
HOMA-IR | |||
Mean (± SD) | 2.00 (1.07) | 3.75 (2.47) | 0.04 |
Median (IQR) | 1.80 (0.98–2.98) | 2.90 (1.90–4.90) | |
Afamin (mg/l) | |||
Mean (± SD) | 176.40 (48.33) | 187.10 (29.19) | 0.50 |
Median (IQR) | 175.80 (158.68–206.39) | 184.72 (160.23–214.95) | |
Gestational age at parturition (days) | |||
Mean (± SD) | 257 (26) | 256 (14) | 0.33 |
Median (IQR) | 266 (252–270) | 260 (243–267) | |
Newborn weight (gram) | |||
Mean (± SD) | 2935 (945) | 2889 (644) | 0.89 |
Median (IQR) | 3170 (2570–3505) | 2915 (2303–3448) | |