Reproductive Biology and Endocrinology

Table 3 Comparison of Treg subpopulations, LAP⁺CD11b⁺ monocytes, and TGF-β concentrations in proliferative and secretory phases (mean ± SD) between endometriosis and control groups

From: Suppressive regulatory T cells and latent transforming growth factor-β-expressing macrophages are altered in the peritoneal fluid of patients with endometriosis

Peritoneal fluid
Proliferative	rTregs (%)	P	eTregs (%)	P	nonTregs (%)	P	LAP+CD11b + Macrophages	P	TGF-β	P
Endometriosis (n = 12)	0.73 ± 0.56	< 0.05	3.9 ± 1.7	< 0.05	7.7 ± 2.7	ns	13.0 ± 14.4	< 0.05	1.12 ± 0.57	< 0.05
Control (n = 10)	0.47 ± 0.60	< 0.05	2.2 ± 1.5	< 0.05	5.8 ± 2.1	ns	80.0 ± 19.7	< 0.05	0.85 ± 0.26	< 0.05
Secretory	rTregs (%)	P	eTregs (%)	P	nonTregs (%)	P	LAP+CD11b + Macrophages	P	TGF-β	P
Endometriosis (n = 16)	0.82 ± 0.75	< 0.05	3.1 ± 2.8	< 0.05	6.0 ± 3.0	ns	12.1 ± 16.4	< 0.05	1.09 ± 0.32	< 0.05
Control (n = 10)	0.30 ± 0.24	< 0.05	1.8 ± 1.3	< 0.05	8.6 ± 1.6	ns	81.3 ± 17.3	< 0.05	0.79 ± 0.26	< 0.05
Peripheral blood
Proliferative	rTregs (%)	P	eTregs (%)	P	nonTregs (%)	P	LAP+CD11b + Monocytes	P
Endometriosis (n = 12)	1.3 ± 0.61	ns	1.2 ± 2.2	ns	2.4 ± 1.9	ns	83.5 ± 16.7	ns
Control (n = 10)	1.3 ± 2.6	ns	1.2 ± 0.8	ns	4.4 ± 2.6	ns	79.2 ± 19.1	ns
Secretory	rTregs (%)	P	eTregs (%)	P	nonTregs (%)	P	LAP+CD11b + Monocytes	P
Endometriosis (n = 12)	2.1 ± 1.6	ns	0.9 ± 1.0	ns	3.0 ± 1.8	ns	80.3 ± 19.7	ns
Control (n = 10)	0.8 ± 2.8	ns	0.8 ± 0.4	ns	3.9 ± 2.2	ns	85.9 ± 11.5	ns

Differences between groups were analyzed by Mann-Whitney U-tests. ns, not significant

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