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Table 3 Comparison of Treg subpopulations, LAP+CD11b+ monocytes, and TGF-β concentrations in proliferative and secretory phases (mean ± SD) between endometriosis and control groups

From: Suppressive regulatory T cells and latent transforming growth factor-β-expressing macrophages are altered in the peritoneal fluid of patients with endometriosis

Peritoneal fluid
Proliferative rTregs (%) P eTregs (%) P nonTregs (%) P LAP+CD11b + Macrophages P TGF-β P
 Endometriosis (n = 12) 0.73 ± 0.56 < 0.05 3.9 ± 1.7 < 0.05 7.7 ± 2.7 ns 13.0 ± 14.4 < 0.05 1.12 ± 0.57 < 0.05
 Control (n = 10) 0.47 ± 0.60 2.2 ± 1.5 5.8 ± 2.1 80.0 ± 19.7 0.85 ± 0.26
Secretory rTregs (%) P eTregs (%) P nonTregs (%) P LAP+CD11b + Macrophages P TGF-β P
 Endometriosis (n = 16) 0.82 ± 0.75 < 0.05 3.1 ± 2.8 < 0.05 6.0 ± 3.0 ns 12.1 ± 16.4 < 0.05 1.09 ± 0.32 < 0.05
 Control (n = 10) 0.30 ± 0.24 1.8 ± 1.3 8.6 ± 1.6 81.3 ± 17.3 0.79 ± 0.26
Peripheral blood
Proliferative rTregs (%) P eTregs (%) P nonTregs (%) P LAP+CD11b + Monocytes P   
 Endometriosis (n = 12) 1.3 ± 0.61 ns 1.2 ± 2.2 ns 2.4 ± 1.9 ns 83.5 ± 16.7 ns   
 Control (n = 10) 1.3 ± 2.6 1.2 ± 0.8 4.4 ± 2.6 79.2 ± 19.1   
Secretory rTregs (%) P eTregs (%) P nonTregs (%) P LAP+CD11b + Monocytes P   
 Endometriosis (n = 12) 2.1 ± 1.6 ns 0.9 ± 1.0 ns 3.0 ± 1.8 ns 80.3 ± 19.7 ns   
 Control (n = 10) 0.8 ± 2.8 0.8 ± 0.4 3.9 ± 2.2 85.9 ± 11.5   
  1. Differences between groups were analyzed by Mann-Whitney U-tests. ns, not significant