Table 1 Comparison of canonical pathways between bovine young and aged endometrial cells
From: Age-associated mRNA expression changes in bovine endometrial cells in vitro
Rank | Name of canonical pathways | zScore | p-value | Molecules |
1 | Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses | 3.16 | 4.68E-04 | IFIH1, IL1A, C5AR1, PIK3CG, DDX58, PIK3R6, C1QA, C1QC, CLEC6A, CCL5, C1QB, CSF2 |
2 | Interferon Signaling | 2.83 | 1.05E-05 | IFIT1, IFIT3, MX1, PSMB8, STAT1, TAP1, IRF1, ISG15 |
3 | Cell Cycle: G2/M DNA Damage Checkpoint Regulation | 2.83 | 1.55E-05 | CDC25B, CDC25C, CKS2, TOP2A, CCNB2, PLK1, AURKA, CDK1, CCNB1 |
4 | Complement System | 2.24 | 9.77E-04 | CFD, ITGB2, C5AR1, C1QA, C1QC, C1QB |
Rank | Name of canonical pathways | zScore | p-value | Molecules |
1 | Mitotic Roles of Polo-Like Kinase | −2.31 | 1.00E-08 | KIF23, CDC25C, ESPL1, CDC20, PTTG1, PRC1, CCNB2, PLK1, CDK1, CCNB1, CDC25B, PLK4, PPP2R2B, KIF11 |