Table 1 Hypothetical population characteristics and diagnostic accuracy measures
Virtual women (cycles) started (N) | 1000 |
|---|---|
Age (y), median (range) | 33 (22–39) |
Cycles abandoned (n); % | 15; 1.5 |
Oocyte retrievals (n); % | 985; 98.5 |
Insemination by ICSI (n); % | 660; 67.0 |
Insemination by IVF (n); % | 325, 33.0 |
Cycles with embryos suitable for transfer or testing (n); % | 870; 87.0 |
Embryos suitable for transfer or testing (N); median (range) | 4476; 5 (1–14) |
Diploid (n); %, median (range) | 3073; 68.7; 3 (0–11) |
Aneuploid (n); %, median (range) | 1403; 31.3; 1 (0–11) |
Embryos transferred, without testing, to achieve a first live birth event (n) | 2204 |
aPositive predictive value [TP/(TP + FP)]; % | 650/683; 95.2 |
bNegative predictive value [TN/(TN + FN)]; % | 615/1521; 40.4 |
Live birth events (n)/fresh transfers (n); % | 244/870; 28.0 |
Miscarriages (n)/fresh clinical pregnancies (n); % | 27/271; 10.0 |