Table 1 List of the common proteins identified in exosomes of ICAR cultured at 1 % O₂ and at 8 % O₂

Protein ID

Name

Gene Name

Biological Process (Total # Gene 69; Total #Function 146)

Molecular function (Total # Gene 69; Total #Function 81)

 A1L523_BOVIN

Copine II (Fragment)

CPNE2

 A3KN51_BOVIN

TSG101 protein

TSG101

Metabolic process

Catalytic activity

 A5D7L1_BOVIN

CLEC11A protein

CLEC11A

Cellular process/Developmental process

Binding/Structural molecule activity

 A5D9D2_BOVIN

Complement component 4 binding protein, alpha chain

C4BPA

 A5PJ69_BOVIN

SERPINA10 protein

SERPINA10

Biological regulation/Metabolic process

Catalytic activity/Enzyme regulator activity

 A5PJE3_BOVIN

Fibrinogen alpha chain

FGA

 A5PK77_BOVIN

SERPINA11 protein

SERPINA11

Biological regulation/Metabolic process

Catalytic activity/Enzyme regulator activity

 A6QLB7_BOVIN

Adenylyl cyclase-associated protein

CAP1

 A6QLL8_BOVIN

Fructose-bisphosphate aldolase

ALDOA

 A6QNZ7_BOVIN

Keratin 10 (Epidermolytic hyperkeratosis; keratosis palmaris et plantaris)

KRT10

 A6QPP2_BOVIN

SERPIND1 protein

SERPIND1

Biological regulation/Metabolic process

Catalytic activity/Enzyme regulator activity

 A6QPR1_BOVIN

PCYOX1 protein

PCYOX1

 LG3BP_BOVIN

Galectin-3-binding protein

LGALS3BP

Apoptotic process/Biological adhesion/Biological regulation/Cellular process/Developmental process/Immune system process/localization/Metabolic process

Catalytic activity/Receptor activity

 A7MB82_BOVIN

C1QTNF3 protein

C1QTNF3

 A7YWB6_BOVIN

LOC539596 protein

LOC539596

 B0JYM4_BOVIN

Tetraspanin

CD63

 B0JYN6_BOVIN

Alpha-2-HS-glycoprotein

AHSG

 B0JYQ0_BOVIN

ALB protein

ALB

 B5B3R8_BOVIN

Alpha S1 casein

CSN1S1

 E1BDG5_BOVIN

Protein Wnt

WNT5A

Biological regulation/Cellular process/Developmental process/Multicellular organismal process/Response to stimulus

Binding

 CBG_BOVIN

Corticosteroid-binding globulin

SERPINA6

Biological regulation/Metabolic process

Catalytic activity/Enzyme regulator activity

 F1MAV0_BOVIN

Fibrinogen beta chain

FGB

 F1MB08_BOVIN

Alpha-enolase

ENO1

 F1MC11_BOVIN

Keratin, type I cytoskeletal 14

KRT14

 F1MM32_BOVIN

Sulfhydryl oxidase

QSOX1

Catalytic activity

 F1MMK9_BOVIN

Protein AMBP

AMBP

 F1MMP5_BOVIN

Inter-alpha-trypsin inhibitor heavy chain H1

ITIH1

 ITA3_BOVIN

Integrin alpha-3

ITGA3

 F1MNW4_BOVIN

Inter-alpha-trypsin inhibitor heavy chain H2

ITIH2

 F1MSZ6_BOVIN

Antithrombin-III

SERPINC1

 F1MTV5_BOVIN

Amino acid transporter

SLC1A5

 F1MW44_BOVIN

Coagulation factor XIII A chain

F13A1

 F1MXJ5_BOVIN

IST1 homolog

IST1

 F1MXX6_BOVIN

Lactadherin

MFGE8

 F1MY85_BOVIN

Complement C5a anaphylatoxin

C5

 F1N045_BOVIN

Complement component C7

C7

 HTRA1_BOVIN

Serine protease HTRA1

HTRA1

Cellular process/Metabolic process

Catalytic activity

 F1N1I6_BOVIN

Gelsolin

GSN

 F6QVC9_BOVIN

Annexin

ANXA5

 G3X6N3_BOVIN

Serotransferrin

TF

 G5E5A9_BOVIN

Fibronectin

FN1

 G5E5V0_BOVIN

Carboxypeptidase N catalytic chain

CPN1

 G8JKX6_BOVIN

Tetraspanin (Fragment)

CD9

 I7CT57_BOVIN

Vitamin D binding protein

 M0QVZ6_BOVIN

Keratin, type II cytoskeletal 5

KRT5

 THRB_BOVIN

Prothrombin

F2

Immune system process/Metabolic process/Response to stimulus

Catalytic activity

 PROC_BOVIN

Vitamin K-dependent protein C (Fragment)

PROC

Response to stimulus

Binding

 KNG2_BOVIN

Kininogen-2

KNG2

 THYG_BOVIN

Thyroglobulin

TG

Metabolic process

Catalytic activity

 HBA_BOVIN

Hemoglobin subunit alpha

HBA

localization/Multicellular organismal process

 HBBF_BOVIN

Hemoglobin fetal subunit beta

localization/Multicellular organismal process

 ALBU_BOVIN

Serum albumin

ALB

localization

 ANXA2_BOVIN

Annexin A2

ANXA2

Developmental process/Metabolic process

 ASSY_BOVIN

Argininosuccinate synthase

ASS1

Cellular process/Metabolic process

Catalytic activity

 APOH_BOVIN

Beta-2-glycoprotein 1

APOH

Cellular process/Immune system process/localization/Metabolic process/Response to stimulus

Catalytic activity/Receptor activity/Transporter activity

 CLUS_BOVIN

Clusterin

CLU

 HSP7C_BOVIN

Heat shock cognate 71 kDa protein

HSPA8

Cellular component organization or biogenesis/Immune system process/Metabolic process/Response to stimulus

 ANXA7_BOVIN

Annexin A7

ANXA7

Metabolic process

 ANX11_BOVIN

Annexin A11

ANXA11

Metabolic process

 A2AP_BOVIN

Alpha-2-antiplasmin

SERPINF2

Biological regulation/Metabolic process

Catalytic activity/Enzyme regulator activity

 A1AT_BOVIN

Alpha-1-antiproteinase

SERPINA1

Biological regulation/Metabolic process

Catalytic activity/Enzyme regulator activity

 GDIB_BOVIN

Rab GDP dissociation inhibitor beta

GDI2

Biological regulation/Cellular process/localization/Metabolic process/Multicellular organismal process

Binding/Catalytic activity/Enzyme regulator activity

 F12AI_BOVIN

Factor XIIa inhibitor

 ITB1_BOVIN

Integrin beta-1

ITGB1

Biological adhesion/Cellular process/Response to stimulus

Receptor activity

 ITIH3_BOVIN

Inter-alpha-trypsin inhibitor heavy chain H3

ITIH3

Biological regulation/Metabolic process

Binding/Catalytic activity/Enzyme regulator activity

 ACTB_BOVIN

Actin, cytoplasmic 1

ACTB

Cellular component organization or biogenesis/Cellular process/Developmental process/localization

Structural molecule activity

 ANXA6_BOVIN

Annexin A6

ANXA6

Metabolic process

 CFAB_BOVIN

Complement factor B

CFB

Biological adhesion/Cellular process/Immune system process/localization/Metabolic process/Response to stimulus

Catalytic activity/Receptor activity/Transporter activity

 TBA1B_BOVIN

Tubulin alpha-1B chain

Cellular process/Developmental process/localization

Structural molecule activity

 LUM_BOVIN

Lumican

LUM

Biological adhesion/Biological regulation/Cellular process/Developmental process/Immune system process/Metabolic process/Multicellular organismal process

Receptor activity

 UPAR_BOVIN

Urokinase plasminogen activator surface receptor

PLAUR

 5NTD_BOVIN

5’-nucleotidase

NT5E

Metabolic process

Catalytic activity

 PGM1_BOVIN

Phosphoglucomutase-1

PGM1

Cellular process/Metabolic process

Catalytic activity

 Q09TE3_BOVIN

Insulin-like growth factor binding protein acid labile subunit

 Q17R18_BOVIN

Adenosine kinase

ADK

 FA5_BOVIN

Coagulation factor V

F5

Biological adhesion/Biological regulation/Cellular process/Developmental process/Immune system process/localization/Metabolic process/Multicellular organismal process/Response to stimulus

Binding/Catalytic activity/Enzyme regulator activity/Receptor activity/Transporter activity

 Q2KIF2_BOVIN

Leucine-rich alpha-2-glycoprotein 1

LRG1

Cellular process/Multicellular organismal process

Receptor activity

 CBPB2_BOVIN

Carboxypeptidase B2

CPB2

Metabolic process

Catalytic activity

 Q2KJ47_BOVIN

EH-domain containing 2

EHD2

Biological regulation/Cellular process/localization/Metabolic process/Multicellular organismal process

Binding/Catalytic activity/Enzyme regulator activity

 TBB5_BOVIN

Tubulin beta-5 chain

TUBB5

Cellular process/Developmental process/localization

Structural molecule activity

 A1BG_BOVIN

Alpha-1B-glycoprotein

A1BG

Cellular process/Immune system process/Response to stimulus

Binding/Receptor activity

 HPT_BOVIN

Haptoglobin

HP

Biological regulation/Immune system process/localization/Metabolic process/Multicellular organismal process/Reproduction/Response to stimulus

Binding/Catalytic activity/Enzyme regulator activity/Receptor activity

 CO3_BOVIN

Complement C3

C3

Biological regulation/Cellular process/Metabolic process/Response to stimulus

Binding/Catalytic activity/Enzyme regulator activity

 Q3MHH8_BOVIN

Alpha-amylase

AMY2A

 SAHH_BOVIN

Adenosylhomocysteinase

AHCY

Cellular process/Metabolic process

Catalytic activity

 CO9_BOVIN

Complement component C9

C9

Cellular process/localization/Metabolic process/Response to stimulus

Catalytic activity/Receptor activity/Transporter activity

 Q3MHW2_BOVIN

F10 protein (Fragment)

F10

 Q3MHZ0_BOVIN

FLOT1 protein (Fragment)

FLOT1

 Q3SYR0_BOVIN

Serpin peptidase inhibitor, clade A (Alpha-1 antiproteinase, antitrypsin), member 7

SERPINA7

 FETA_BOVIN

Alpha-fetoprotein

AFP

Developmental process/localization

 Q3SZH5_BOVIN

Angiotensinogen

AGT

 HEMO_BOVIN

Hemopexin

HPX

localization

 Q3SZZ9_BOVIN

FGG protein

FGG

 PGK1_BOVIN

Phosphoglycerate kinase 1

PGK1

Metabolic process

Catalytic activity

 Q3T101_BOVIN

IGL@ protein

IGL@

 G6PI_BOVIN

Glucose-6-phosphate isomerase

GPI

Metabolic process

Catalytic activity

 Q3ZBX0_BOVIN

Basigin

BSG

 Q3ZC87_BOVIN

Pyruvate kinase (Fragment)

PKM2

 Q3ZCI4_BOVIN

6-phosphogluconate dehydrogenase, decarboxylating

PGD

Metabolic process

Catalytic activity

 FETUB_BOVIN

Fetuin-B

FETUB

 EHD1_BOVIN

EH domain-containing protein 1

EHD1

Biological regulation/Cellular process/localization/Metabolic process/Multicellular organismal process

Binding/Catalytic activity/Enzyme regulator activity

 HPPD_BOVIN

4-hydroxyphenylpyruvate dioxygenase

HPD

Metabolic process

Catalytic activity

 Q5EA67_BOVIN

Inter-alpha (Globulin) inhibitor H4 (Plasma Kallikrein-sensitive glycoprotein)

ITIH4

 Q5GN72_BOVIN

Alpha-1-acid glycoprotein

agp

 BHMT1_BOVIN

Betaine--homocysteine S-methyltransferase 1

BHMT

Cellular process/Metabolic process

Catalytic activity

 Q5J801_BOVIN

Endopin 2B

 Q6T182_BOVIN

Sex hormone-binding globulin (Fragment)

SHBG

 A2MG_BOVIN

Alpha-2-macroglobulin

A2M

Biological regulation/Cellular process/Immune system process/Metabolic process/Response to stimulus

Binding/Catalytic activity/Enzyme regulator activity

 PEDF_BOVIN

Pigment epithelium-derived factor

SERPINF1

Biological regulation/Metabolic process

Catalytic activity/Enzyme regulator activity

 CHIA_BOVIN

Acidic mammalian chitinase

CHIA

Immune system process/Metabolic process/Response to stimulus

Binding/Catalytic activity

 IPSP_BOVIN

Plasma serine protease inhibitor

SERPINA5

Biological regulation/Metabolic process

Catalytic activity/Enzyme regulator activity

 SPA31_BOVIN

Serpin A3-1

SERPINA3-1

Biological regulation/Metabolic process

Catalytic activity/Enzyme regulator activity

 V6F9A2_BOVIN

Apolipoprotein A-I preproprotein

APOA1

Protein ID

Name

Gene Name

Biological Process (Total # Gene 22; Total #Function 49)

Molecular function (Total # Gene 22; Total #Function 28)

 G3X6T9_BOVIN

Flotillin-2 (Fragment)

FLOT2

 TSP1_BOVIN

Thrombospondin-1

THBS1

 F1N2L9_BOVIN

4-trimethylaminobutyraldehyde dehydrogenase

ALDH9A1

 E1B9F6_BOVIN

Elongation factor 1-alpha

EEF1A1

 APOE_BOVIN

Apolipoprotein E

APOE

Apoptotic process/Biological regulation/Cellular component organization or biogenesis/Cellular process/Developmental process/Growth/localization/Metabolic process/Multicellular organismal process/Response to stimulus

Binding/Catalytic activity/ Enzyme regulator activity/Transporter activity

 G1K1R6_BOVIN

Galactokinase

GALK1

 G3P_BOVIN

Glyceraldehyde-3-phosphate dehydrogenase

GAPDH

Metabolic process

Catalytic activity

 Q0P5B0_BOVIN

Arrestin domain containing 1

ARRDC1

 RL40_BOVIN

Ubiquitin-60S ribosomal protein L40

UBA52

Metabolic process

Binding/Structural molecule activity

 A5D9B6_BOVIN

Syntenin

SDCBP

 Q8HZY1_BOVIN

Serine protease inhibitor clade E member 2

SERPINE2

 Q5E962_BOVIN

Aldo-keto reductase family 1, member B1

AKR1B1

 A7MBH9_BOVIN

GNAI2 protein

GNAI2

Biological regulation/Cellular process/Metabolic process/Response to stimulus

Binding/Catalytic activity

 GBB2_BOVIN

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

GNB2

Cellular process/Metabolic process/Multicellular organismal process

Binding/Catalytic activity

 I6YIV1_BOVIN

Annexin

 F16P1_BOVIN

Fructose-1,6-bisphosphatase 1

FBP1

Metabolic process

 F1N3Q7_BOVIN

Apolipoprotein A-IV

APOA4

 AK1A1_BOVIN

Alcohol dehydrogenase [NADP(+)]

AKR1A1

localization/Metabolic process

Catalytic activity/Transporter activity

 A5D784_BOVIN

CPNE8 protein

CPNE8

localization

 HS90A_BOVIN

Heat shock protein HSP 90-alpha

HSP90AA1

Immune system process/Metabolic process/Response to stimulus

 Q1JPA2_BOVIN

Eukaryotic translation elongation factor 1 gamma (Fragment)

EEF1G

 SERA_BOVIN

D-3-phosphoglycerate dehydrogenase

PHGDH

Metabolic process

Catalytic activity

 Q3T085_BOVIN

OGN protein

OGN

 A8DBT6_BOVIN

Monocyte differentiation antigen CD14

CD14

 A5PK73_BOVIN

Fructose-bisphosphate aldolase

ALDOB

 G5E5U7_BOVIN

S-adenosylmethionine synthase

MAT1A

 F1N2W0_BOVIN

Prostaglandin reductase 1

PTGR1

 IF4A1_BOVIN

Eukaryotic initiation factor 4A-I

EIF4A1

Biological regulation/Metabolic process

Binding/Catalytic activity/Translation regulator activity

 Q05B55_BOVIN

IGK protein

IGK

 F1N1D4_BOVIN

Protein tweety homolog

TTYH3

localization

Transporter activity

 A4FV94_BOVIN

KRT6A protein

KRT6A

 RGN_BOVIN

Regucalcin

RGN

Cellular process/localization/Metabolic process

Binding/Catalytic activity

 1433E_BOVIN

14-3-3 protein epsilon

YWHAE

Cellular process

 Q2HJB6_BOVIN

Procollagen C-endopeptidase enhancer

PCOLCE

Biological adhesion/Biological regulation/Cellular process/Developmental process/Immune system process/localization/Metabolic process/Multicellular organismal process/Response to stimulus

Binding/Catalytic activity/Enzyme regulator activity/Receptor activity/Transporter activity

 B8YB76_BOVIN

Homogentisate 1,2-dioxygenase

HGD

 DHSO_BOVIN

Sorbitol dehydrogenase

SORD

Metabolic process

Catalytic activity

 HS71A_BOVIN

Heat shock 70 kDa protein 1A

HSPA1A

Cellular component organization or biogenesis/Immune system process/Metabolic process/Response to stimulus

 Q3ZBQ9_BOVIN

APOM protein

APOM

 PYGL_BOVIN

Glycogen phosphorylase, liver form

PYGL

Metabolic process

Catalytic activity

 A6QP30_BOVIN

CPN2 protein

CPN2

Cellular process/Multicellular organismal process

Receptor activity

 ARF3_BOVIN

ADP-ribosylation factor 3

ARF3

Cellular process/localization/Metabolic process

Binding/Catalytic activity

 G3MYH4_BOVIN

Tetraspanin (Fragment)

CD81

 ACTC_BOVIN

Actin, alpha cardiac muscle 1

ACTC1

Cellular component organization or biogenesis/Cellular process/Developmental process/localization

Structural molecule activity

 GALM_BOVIN

Aldose 1-epimerase

GALM

Metabolic process

Catalytic activity

 TSN6_BOVIN

Tetraspanin-6

TSPAN6

Biological adhesion/Cellular process/Immune system process/Multicellular organismal process/Reproduction/Response to stimulus

Binding/Receptor activity

 Q3ZC83_BOVIN

Solute carrier family 29 (Nucleoside transporters), member 1

SLC29A1

localization/Metabolic process

Transporter activity

 B4GA1_BOVIN

Beta-1,4-glucuronyltransferase 1

B4GAT1

Metabolic process

Catalytic activity

 ADA10_BOVIN

Disintegrin and metalloproteinase domain-containing protein 10

ADAM10

Apoptotic process/Developmental process/Reproduction

 A6QR28_BOVIN

Phosphoserine aminotransferase

PSAT1

Metabolic process

Catalytic activity

 Q1JPB6_BOVIN

Acetyl-Coenzyme A acetyltransferase 2

ACAT2

 DDBX_BOVIN

Dihydrodiol dehydrogenase 3

localization/Metabolic process

Catalytic activity/Transporter activity

 A2VE11_BOVIN

IGSF8 protein

IGSF8

 F1MS32_BOVIN

Apolipoprotein D

APOD

 A6QP64_BOVIN

VPS37B protein (Fragment)

VPS37B

 Q2KIW4_BOVIN

Lecithin-cholesterol acyltransferase

LCAT

Metabolic process

Catalytic activity

 GBB1_BOVIN

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

GNB1

Cellular process/Metabolic process

Binding/Catalytic activity

 GNA11_BOVIN

Guanine nucleotide-binding protein subunit alpha-11

GNA11

Biological regulation/Cellular process/Metabolic process/Response to stimulus

Catalytic activity

 Q17QK4_BOVIN

Epoxide hydrolase 2, cytoplasmic

EPHX2

 K2C7_BOVIN

Keratin, type II cytoskeletal 7

KRT7

Cellular component organization or biogenesis/Cellular process/Developmental process

Structural molecule activity

 CLIC1_BOVIN

Chloride intracellular channel protein 1

CLIC1

Biological regulation/Cellular process/Metabolic process/Response to stimulus

Binding/Catalytic activity/Structural molecule activity/Translation regulator activity

 Q08DW4_BOVIN

Mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)

MASP1

 B4GT1_BOVIN

Beta-1,4-galactosyltransferase 1

B4GALT1

 A5D7E6_BOVIN

Tetraspanin

CD82

Cellular process/Response to stimulus

Binding/Receptor activity

 A5D973_BOVIN

Alpha isoform of regulatory subunit A, protein phosphatase 2

PPP2R1A

 E1B726_BOVIN

Plasminogen

PLG

 G5E6I9_BOVIN

Histone H2B

LOC101904777

Cellular component organization or biogenesis/Cellular process/Metabolic process

Binding

 ADIPO_BOVIN

Adiponectin

ADIPOQ

 F1MBC5_BOVIN

Coagulation factor IX

F9

 A2VDL2_BOVIN

Solute carrier family 2 (Facilitated glucose transporter), member 3

SLC2A3

 VPS4B_BOVIN

Vacuolar protein sorting-associated protein 4B

VPS4B

 G3X8B1_BOVIN

Peptidyl-prolyl cis-trans isomerase

LOC613401

 K4JB97_BOVIN

Alpha-2-macroglobulin variant 4

A2M

 ACTG_BOVIN

Actin, cytoplasmic 2

ACTG1

Cellular component organization or biogenesis/Cellular process/localization

Structural molecule activity

 Q1JPG7_BOVIN

Pyruvate kinase

PKLR

 GTR1_BOVIN

Solute carrier family 2, facilitated glucose transporter member 1

SLC2A1

 F1N342_BOVIN

Protein tweety homolog

TTYH2

localization

Transporter activity

 ADHX_BOVIN

Alcohol dehydrogenase class-3

ADH5

Metabolic process

Catalytic activity

 URP2_BOVIN

Fermitin family homolog 3

FERMT3

 E1B7N2_BOVIN

Histone H4

HIST1H4I

Cellular component organization or biogenesis/Cellular process/Metabolic process

Binding

 EF2_BOVIN

Elongation factor 2

EEF2

Biological regulation/Metabolic process

Binding/Translation regulator activity

 KLKB1_BOVIN

Plasma kallikrein

KLKB1

Biological regulation/localization/Metabolic process/Response to stimulus

Binding/Catalytic activity/Enzyme regulator activity/Receptor activity

 ESTD_BOVIN

S-formylglutathione hydrolase

ESD

Metabolic process

Catalytic activity

 SEPR_BOVIN

Prolyl endopeptidase FAP

FAP

Cellular process/Immune system process/localization/Metabolic process/Multicellular organismal process / Response to stimulus

Binding/Catalytic activity

 Q5EA54_BOVIN

Solute carrier family 3 (Activators of dibasic and neutral amino acid transport), member 2

SLC3A2

 Q1JPD9_BOVIN

G protein-coupled receptor, family C, group 5, member B

GPRC5B

Cellular process

Receptor activity

 F1MS05_BOVIN

Aconitate hydratase

ACO1

 F1MJ12_BOVIN

Complement C1s subcomponent

C1S

 CNDP2_BOVIN

Cytosolic non-specific dipeptidase

CNDP2

Metabolic process

Catalytic activity

 Q2TBQ1_BOVIN

Coagulation factor XIII, B polypeptide

F13B

Biological adhesion/Cellular process/Immune system process/localization/Metabolic process/Response to stimulus

Catalytic activity/Receptor activity/Transporter activity

 Q1JP72_BOVIN

Colony stimulating factor 1 receptor

CSF1R

 Q0VD03_BOVIN

CD44 antigen

CD44

 G3X6Y4_BOVIN

Osteomodulin

OMD

 GAMT_BOVIN

Guanidinoacetate N-methyltransferase

GAMT

 VWA1_BOVIN

von Willebrand factor A domain-containing protein 1

VWA1

 SERC3_BOVIN

Serine incorporator 3

SERINC3

 Q862H8_BOVIN

Similar to 40S ribosomal protein SA (P40) (Fragment)

 A8E4P3_BOVIN

STOM protein

STOM

 F1MHP6_BOVIN

Adenylosuccinate lyase

ADSL

 E1BMG9_BOVIN

10-formyltetrahydrofolate dehydrogenase

ALDH1L1

Metabolic process

Catalytic activity

 Q705V4_BOVIN

Kappa-casein (Fragment)

csn3

 G3X6Q8_BOVIN

Pentraxin-related protein PTX3

PTX3

 K7QEL2_BOVIN

MHC class I antigen

BoLA

 TCPQ_BOVIN

T-complex protein 1 subunit theta

CCT8

Cellular component organization or biogenesis / Metabolic process

 F1N6Z0_BOVIN

26S proteasome non-ATPase regulatory subunit 5

PSMD5

 ARLY_BOVIN

Argininosuccinate lyase

ASL

Metabolic process

Catalytic activity

 E1BNG2_BOVIN

alpha-1,2-Mannosidase

MAN1A1

Metabolic process

 F1MU79_BOVIN

Peptidyl-prolyl cis-trans isomerase FKBP4

FKBP4

 DPYL2_BOVIN

Dihydropyrimidinase-related protein 2

DPYSL2

Metabolic process

Catalytic activity

 PRS23_BOVIN

Serine protease 23

PRSS23

 B0JYN1_BOVIN

Cathepsin L2

CTSL2

 A4FV99_BOVIN

FCNB protein

FCNB

 A7YW37_BOVIN

CD58 protein (Fragment)

CD58

Immune system process/Response to stimulus

Binding

 F1MTP5_BOVIN

WD repeat-containing protein 1

WDR1

 A7E3D0_BOVIN

CCDC45 protein (Fragment)

CCDC45

 Q0VCK1_BOVIN

Myeloid-associated differentiation marker

MYADM

 A1L570_BOVIN

Ephrin-B1

EFNB1

Biological regulation/Cellular component organization or biogenesis/Cellular process/Developmental process/locomotion/Multicellular organismal process/Response to stimulus

Binding

 F1N049_BOVIN

Actin-related protein 3 (Fragment)

ACTR3

 PAI1_BOVIN

Plasminogen activator inhibitor 1

SERPINE1

Biological regulation/Metabolic process

Catalytic activity/Enzyme regulator activity

 Q3ZC30_BOVIN

Sulfotransferase

SULT1E1

 COL11_BOVIN

Collectin-11

COLEC11

Biological regulation/Immune system process/Multicellular organismal process

 MPZL1_BOVIN

Myelin protein zero-like protein 1

MPZL1

Cellular process/localization

Transporter activity

 G5E595_BOVIN

Lys-63-specific deubiquitinase BRCC36

BRCC3

 O18977_BOVIN

Tenascin-X

TN-X

 A6H7D3_BOVIN

KRT18 protein (Fragment)

KRT18

 J9ZXG5_BOVIN

Integrin alpha V subunit

 B0JYN3_BOVIN

L-lactate dehydrogenase

LDHB

 MB211_BOVIN

Protein mab-21-like 1

MAB21L1

 E1B7R4_BOVIN

Eukaryotic translation initiation factor 3 subunit A

EIF3A

Biological regulation/Metabolic process

Binding/Translation regulator activity

Protein ID

Name

Gene Name

Biological Process (Total # Gene 22; Total #Function 49)

Molecular function (Total # Gene 22; Total #Function 28)

 F1MMD7_BOVIN

Inter-alpha-trypsin inhibitor heavy chain H4

ITIH4

 F1N3A1_BOVIN

Thrombospondin-1

THBS1

 PLMN_BOVIN

Plasminogen

PLG

Biological regulation/localization/Metabolic process/Response to stimulus

Binding/Catalytic activity/Enzyme regulator activity/Receptor activity

 F1MYN5_BOVIN

Fibulin-1

FBLN1

Cellular process/Developmental process

Binding

 F1MNV5_BOVIN

Kininogen-1

KNG1

 EF1A1_BOVIN

Elongation factor 1-alpha 1

EEF1A1

Biological regulation/Metabolic process

Binding/Catalytic activity/Translation regulator activity

 ITAV_BOVIN

Integrin alpha-V

ITGAV

Biological adhesion

 F1MK44_BOVIN

Integrin alpha-5

ITGA5

 TTHY_BOVIN

Transthyretin

TTR

localization

Transporter activity

 F1MC45_BOVIN

Complement factor H (Fragment)

CFH

 J9QD97_BOVIN

Periostin variant 9

 ACTS_BOVIN

Actin, alpha skeletal muscle

ACTA1

Cellular component organization or biogenesis/Cellular process/Developmental process/localization

Structural molecule activity

 E1B9K1_BOVIN

Polyubiquitin-C

UBC

 A7YWR0_BOVIN

Apolipoprotein E

APOE

 FA9_BOVIN

Coagulation factor IX

F9

Apoptotic process/Biological regulation/Developmental process/Immune system process/ localization/Metabolic process/Multicellular organismal process/Response to stimulus

Binding/Catalytic activity/Enzyme regulator activity/Receptor activity

 COMP_BOVIN

Cartilage oligomeric matrix protein

COMP

 K2C80_BOVIN

Keratin, type II cytoskeletal 80

KRT80

Cellular component organization or biogenesis/Cellular process/Developmental process

Structural molecule activity

 TRFE_BOVIN

Serotransferrin

TF

localization/Metabolic process

Catalytic activity

 K4JDR8_BOVIN

Alpha-2-macroglobulin variant 5

A2M

 Q32P72_BOVIN

CP protein (Fragment)

CP

 J9ZW47_BOVIN

Integrin beta

 F1MM86_BOVIN

Complement component C6

C6

 E1BI02_BOVIN

Fibromodulin

FMOD

 VNN1_BOVIN

Pantetheinase

VNN1

Biological adhesion/Cellular process/Metabolic process

Catalytic activity

 G3X807_BOVIN

Histone H4 (Fragment)

Cellular component organization or biogenesis/Cellular process/Metabolic process

Binding

 MOT1_BOVIN

Monocarboxylate transporter 1

SLC16A1

Cellular process/localization

Transporter activity

 TF_BOVIN

Tissue factor

F3

Biological regulation/Cellular process/Response to stimulus

Binding/Receptor activity

 HS71L_BOVIN

Heat shock 70 kDa protein 1-like

HSPA1L

Metabolic process/Response to stimulus

 Q3ZCA7_BOVIN

Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3

GNAI3

Biological regulation/Cellular process/Metabolic process/Response to stimulus

Binding/Catalytic activity

 IDHC_BOVIN

Isocitrate dehydrogenase [NADP] cytoplasmic

IDH1

 Q1PBC8_BOVIN

CD14 (Fragment)

 F1MJJ8_BOVIN

Radixin (Fragment)

RDX

 IF4A2_BOVIN

Eukaryotic initiation factor 4A-II

EIF4A2

Biological regulation/Metabolic process

Binding/Catalytic activity/Translation regulator activity

 C1QB_BOVIN

Complement C1q subcomponent subunit B

C1QB

 A6QPD4_BOVIN

LOC790886 protein

LOC790886

 CTL2_BOVIN

Choline transporter-like protein 2

SLC44A2

localization

Transporter activity

 HPCL1_BOVIN

Hippocalcin-like protein 1

HPCAL1

Cellular process/Multicellularorganismal process

 Q24K07_BOVIN

Vacuolar protein sorting 11 homolog (S. cerevisiae)

VPS11

 Q5H9M6_BOVIN

Dynein heavy chain (Fragment)

Bv2

 Q864S1_BOVIN

Cathepsin C (Fragment)

 Q4ZJS0_BOVIN

MHC class I antigen (Fragment)

BoLA-N

 Q58CZ4_BOVIN

Flotillin 2

FLOT2

 MBL2_BOVIN

Mannose-binding protein C

MBL

Binding

 TM214_BOVIN

Transmembrane protein 214

TMEM214

 Q8MIR1_BOVIN

Nicotinic acetylcholine receptor beta 2 subunit (Fragment)

CHRNB2

 Q5E9W1_BOVIN

CDC45-like

CDC45L