Fig. 2From: Relationship between Advanced Glycation End Products and Steroidogenesis in PCOSPotential effect of AGE-RAGE binding on steroidogenic enzymes. The binding of AGEs to RAGE induces several steroidogenic enzymes which might lead to increase in testosterone production. Green color represents induction. StAR: Steroidogenic Acute Regulatory protein, P450scc: cholesterol side chain cleavage enzyme, CYP17A1: 17 alpha-hydroxylase and 17, 20 lyase, and 3β-HSD: 3β hydroxysteroid dehydrogenase Back to article page