Fig. 2

Implanted myomas presented with higher ERα, PR, vimentin, VEGF and MVD compared with pre-xenografted myoma and non-implanted myoma. a Implanted and non-implanted myoma fragments at sacrifice 3 weeks later. Yellow arrows indicate implanted myoma; white arrows indicate non-implanted myoma. b Implantations and non-implantations in each mouse at sacrifice. 3 of 5 SCID mice developed implanted uterine myoma. c H&E, and IHC stainings for ERα, PR, Ki67, vimentin, VEGF, and CD34. Original magnification: ×400; the scale bars represent 400 μm. d–j IHS of three groups. Implanted myoma presented with higher ERα, PR, VEGF, MVD cell density and Ki-67 expressions compared with pre-xenografted uterine myoma and non-implanted myoma. UM = pre-xenografted uterine myoma, MVD = microvessel density, Imp = implanted, Non-imp = non-implanted, *P < 0.05