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Table 1 Comparison of embryo ploidy between two PGS 2.0 assessments

From: Accuracy of preimplantation genetic screening (PGS) is compromised by degree of mosaicism of human embryos

Pat.#

Emb#

Biopsy #

Original PGS analysis (all embryos reported as abnormal)

Repeat PGS analysisa (multiple biopsies)

1

A1

1

45, XY, -18b

Normal 46, XX

2

A2

1

Complex aneuploidb

XY, +10, -18q

 

A3

2

 

XY, +11, +16, -21

 

A4

3

 

XX, -3q

3

A5

1

46, XY, +3, -11, +15, -14b

XX, -2

 

A6

2

 

Normal 46XX

 

A7

3

 

45, XY, -18

 

A8

4

 

Normal 46,XX

4

B1

1

46,XY, +3, -11b

45, XY, -14

 

B2

2

 

45, XY, -14

 

B3

3

 

45, XY, -14

 

B4

4

 

45, XY, -14

5

B5

1

47,XY, +19b

47, XY, +3

 

B6

2

 

47, XY, +3

 

B7

3

 

47, XY, +3

 

B8

4

 

Normal 46, XY

6

C1

1

45, XX, -1b

Normal 46, XX

 

C2

2

 

Normal 46, XX

 

C3

3

 

Normal 46, XX

7

C4

1

47, XY, +19b

Normal 46, XY

 

C5

2

 

Normal 46, XY

 

C6

3

 

Normal 46, XY

8

C7

1

47, XY, +19c

Normal 46, XY

 

C8

2

 

Normal 46, XY

 

C9

3

 

Normal 46, XY

 

C10

4

 

Normal 46, XY

9

D1

1

Complex aneuploidc

Normal 46, XY

 

D2

2

 

47, +18

10

D3

1

Complex aneuploidc

47, XY, +8q, -15, +16

 

D4

2

 

46, XY, -15, +16

 

D5

3

 

46, XY, -15, +16

 

D6

4

 

46, XY, -15, +16

 

D7

5

 

46, XY, -15, +16

11

D8

1

46, XX, +14, -15c

46, XX, +14, -15

 

D9

2

 

46, XX, +14, -15

 

D10

3

 

46, XX, +14, -15

 

D11

4

 

46, XX, +14, -15

  1. Pat# patient number, Emb# embryo number; The diagnostic platforms utilized by the various PGS laboratories are described under Methods: aaCGH, bqPCR and caray CGH