From: Biosimilar FSH preparations- are they identical twins or just siblings?
Bemfola [23] | GF [23] | GF [24] | Ovaleap [24] | |||||
---|---|---|---|---|---|---|---|---|
# of patients | % of patients treated | # of patients | % of patients treated | # of patients | % of patients treated | # of patients | % of patients treated | |
# of patients | 249 | 123 | 146 | 153 | ||||
BMI (kg/m2) | 22.7 | 22.4 | 22.6 | 22.8 | ||||
FSH (IU) | 6.9 | 6.9 | 7.3 | 7 | ||||
Duration of stimulation (days) | 10.6 | 10.7 | 9.7 | 9.3 | ||||
Total dose of FSH used | 1555 | 1569 | 1614 | 1536 | ||||
E2 (pmol/L) | 8982 | 7704 | 9534 | 10070 | ||||
OHSS | 14 | 0.056 | 4 | 0.032 | 4 | 0.027 | 7 | 0.045 |
# oocyte | 10.7 | 10.4 | 12.1 | 12.2 | ||||
#ET | 1.5 | 1.6 | NA | NA | ||||
FR (%) | 66.1 | 64 | NA | NA | ||||
IR (%) | 31.8 | 36.7 | NA | NA | ||||
Biochemical pregnancy | 116 | 0.465 | 60 | 0.487 | 60 | 0.410 | 58 | 0.379 |
Clinical pregnancy | 90 | 0.361 | 55 | 0.447 | 52 | 0.356 | 43 | 0.281 |
Ongoing pregnancy | 84 | 0.337 | 51 | 0.414 | 49 | 0.335 | 42 | 0.274 |
LBR | NA | NA | 47 | 0.321 | 41 | 0.267 | ||
Chemical pregnancy | 26 | 0.104 | 5 | 0.040 | 8 | 0.054 | 15 | 0.098 |