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Table 2 Comparisons of APOB concentrations in human FF according to IVF/ICSI outcomes

From: Apolipoprotein B is regulated by gonadotropins and constitutes a predictive biomarker of IVF outcomes

FF related to n / number of FF analyzed (%) APOB (ng/ml)   p-value
Mean ± SD [95 % CI]  
Oocyte 143 / 201 (71.1) 271.0 ± 181.8 [240.9; 301.0] p = 0.001
Empty zona pellucida (no oocyte) 58 / 201 (28.9) 179.0 ± 181.3 [131.8; 227.2]  
Normal fertilized oocytes 107 / 201 (53.2) 279.8 ± 168 [247.6; 312.0] p = 0.004
No fertilized oocytes 23 / 201 (11.4) 162.6 ± 192.5 [79.4; 245.8]  
Embryo 92 / 201 (45.8) 294.3 ± 159.8 [261.2; 327.4] p < 0.001
No embryo 109 / 201(54.2) 202.6 ± 196.5 [165.3; 239.9]  
Early cleavage 22 / 92 (23.9) 352.1 ± 192.6 [266.7; 437.5] NS
No early cleavage 70 / 92 (76.1) 276.1 ± 144.9 [241.6; 310.7]  
Top quality embryo 45 / 92 (48.9) 322.1 ± 205.2 [260.4; 383.7] NS
No top quality embryo 47 / 92 (51.1) 267.7 ± 93.6 [240.2; 295.2]  
  1. Values are reported by the number of variable (n) / number of FF analyzed (percentage of the total). The comparisons were performed using Student’s t-test. SD Standard Deviation, FF Follicular Fluid, NS No significant