Reproductive Biology and Endocrinology

Table 1 Effect of BMP-4 in IVG medium on the growth of OGCs from early antral follicles

From: Effect of bone morphogenetic protein-4 on in vitro growth, steroidogenesis and subsequent developmental competence of the oocyte-granulosa cell complex derived from bovine early antral follicles

IVG culture (day)	BMP-4 (ng/ml)	% of OGC viability (n)	Granulosa cell
IVG culture (day)	BMP-4 (ng/ml)	% of OGC viability (n)	Counting (× 10³ cells)	% of viability (n)	Diameter (μm)
0	-	100.0^a (30)	2.0 ± 0.5^c	88.7 ± 2.8^b (30)	9.3 ± 1.1^c
12	0	67.8^b (242)	85.0 ± 33.7^a	92.8 ± 3.4^a (26)	12.0 ± 0.8^a
	10	70.4^b (250)	69.0 ± 23.5^ab	93.2 ± 2.9^a (25)	11.2 ± 0.9^b
	50	48.2^c (247)	49.6 ± 12.4^b	93.7 ± 3.2^a (14)	11.0 ± 0.9^b

Data are presented as the mean ± standard deviation
^abcValues with different superscripts in the same column are significantly different (p < 0.05)

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ISSN: 1477-7827

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