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Table 1 Effect of BMP-4 in IVG medium on the growth of OGCs from early antral follicles

From: Effect of bone morphogenetic protein-4 on in vitro growth, steroidogenesis and subsequent developmental competence of the oocyte-granulosa cell complex derived from bovine early antral follicles

IVG culture (day) BMP-4 (ng/ml) % of OGC viability (n) Granulosa cell
Counting (× 103 cells) % of viability (n) Diameter (μm)
0 - 100.0a (30) 2.0 ± 0.5c 88.7 ± 2.8b (30) 9.3 ± 1.1c
12 0 67.8b (242) 85.0 ± 33.7a 92.8 ± 3.4a (26) 12.0 ± 0.8a
10 70.4b (250) 69.0 ± 23.5ab 93.2 ± 2.9a (25) 11.2 ± 0.9b
50 48.2c (247) 49.6 ± 12.4b 93.7 ± 3.2a (14) 11.0 ± 0.9b
  1. Data are presented as the mean ± standard deviation
  2. abcValues with different superscripts in the same column are significantly different (p < 0.05)