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Fig. 3 | Reproductive Biology and Endocrinology

Fig. 3

From: Very small embryonic-like stem cells (VSELs) detected in azoospermic testicular biopsies of adult survivors of childhood cancer

Fig. 3

Relative mRNA expression of pluripotent markers (Oct-4A/Oct-4B, Nanog, Sox-2) and germ cell specific marker (Boule) by qRT-PCR in azoospermic testes compared to normal testicular sample. Note that the pluripotent markers persist (unaltered or slightly increased) whereas the germ cell marker was markedly reduced in azoospermic testicular sample. Pluripotent transcripts expression for various patients (P1, P2 and P3) is represented separately as relative expression normalized to 18S RNA. Error bars represent standard deviation between two technical replicates for the same patient sample

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