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Table 2 Clinical diagnosis and treatment of 12 patients with first trimester Cesarean scar pregnancies

From: First-trimester diagnosis and management of Cesarean scar pregnancies after in vitro fertilization-embryo transfer: a retrospective clinical analysis of 12 cases

Case no.

Gestational age at diagnosis (weeks)

Type of pregnancy

Gestational sac of CSP(mm)

CRL(mm)

Viability

Myometrtrial thickness(mm)

Type of treatment

Success

Time after treatment for β-hCG to reach normal level (days)

Time after treatment for subtrophobla-stic flow to disappear (days)

Follow-up information

1

6 + 3

CSP

22 × 12

3.6

Viable

2.9

TVS guidance local MTX + Systemic MTX

No

-

-

Laparotomy with wedge excision of CSP at 6 W+ due to massive vaginal bleeding and abdominal pain after MTX treatment

2

5 + 3

CSP

6 × 5

no

Non-viable

4.7

Hysteroscopy

Yes

38

42

Cured, no attempt at another pregnancy

3

6 + 2

CSP

18 × 14

2

Viable

4.5

Systemic MTX + TVS guidance D&C

Yes

52

49

Cured, waiting for another IVF treatment

4

5 + 6

CSP

16 × 10

no

Non-viable

3.7

Hysteroscopy

Yes

32

41

Cured, no attempt at another pregnancy

5

7 + 0

CSP

27 × 17

5.4

Viable

3.3

UAE + Hysteroscopy

Yes

44

57

Cured, no attempt at another pregnancy

6

5 + 4

CSP

4.8 × 3.4

no

Non-viable

4.9

HIFU + Hysteroscopic guidance suction curettage

Yes

26

30

Cured, no attempt at another pregnancy

7

6 + 5

Heterotopic

16 × 7

no

Non-viable

5.9

Expectant

Yes

-

77

Cesarean section due to massive hemorrhage caused by complete placenta previa at 35 W+,ectopic mass (21 × 14 mm) was removed at the same time, and a healthy boy weighing 2.6 kg was born

8

5 + 6

Heterotopic

19 × 6

no

Non-viable

2.7

Expectant

Yes

-

52

TVS guidance D&C due to IUP termination at 13 W+

9

7 + 4

Heterotopic

20 × 12

3

Non-viable

5.2

Expectant

Yes

-

96

Second trimester abortion (6 months’ gestation) of IUP

10

6 + 3

Heterotopic

4 × 3

no

Non-viable

7.4

Expectant

Yes

-

69

Cesarean section due to premature rupture of membranes at 36 W+, a healthy girl weighing 2.9 kg was born; Scar mass disappeared at 22 W+

11

6 + 3

Heterotopic

39 × 8

3.4

Viable

4.2

TVS guidance local KCL

Yes

-

44

TVS guidance D&C due to IUP termination at 14 W+

12

7 + 1

Heterotopic

27 × 10

no

Non-viable

4.1

Expectant

Yes

-

118

IUP was 18 W+ gestation at the time of writing; Retained ectopic mass (32 × 27 mm)

  1. CSP Cesarean scar pregnancy, CRL crown—rump length, TVS transvaginal ultrasound guidance, MTX methotrexate, D&C dilatation and curettage, UAE uterine artery embolization, HIFU high intensity focused ultrasound, KCL potassium chloride, IUP intrauterine pregnancy