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Table 2 Immunohistochemistry analysis in ovarian follicles for angiogenesis (VEGF), cellular proliferation (Ki-67) and apoptosis (cleaved-caspase-3 and TUNEL), according to treatment with Adipose Tissue-Derived Stem Cells from transgenic rats for Green Fluorescent Protein (rASC-GFP), in topic and autologous grafted ovary

From: Does adipose tissue-derived stem cell therapy improve graft quality in freshly grafted ovaries?

 

Topic

Graft

 

Vehicle

rASC-GFP

Vehicle

rASC-GFP

VEGF

13.58 ± 4.4

27.13 ± 11.1*

25.46 ± 9.4

41.9 ± 11.7

Ki67

2.46 ± 0.55

2.12 ± 0.7

2.44 ± 1.5

1.72 ± 0.38

Caspase-3

4.23 ± 2.5

6.39 ± 2.9

6.97 ± 5.6

6.18 ± 3.44

TUNEL

0.03 ± 0.03

0.04 ± 0.08

0.13 ± 0.12

0.04 ± 0.05

  1. Data are shown as percentage of positively stained follicle cells per area (arbitrary unity/mm2). VEGF Vascular Endothelial Grown Factor, TUNEL Terminal deoxynucleotidyl transferase (TdT)-mediated dUTP nick-end
  2. Data were shown in mean ± SD; Student t-test; *p = 0.0352 vs. Vehicle
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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