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Table 2 Immunohistochemistry analysis in ovarian follicles for angiogenesis (VEGF), cellular proliferation (Ki-67) and apoptosis (cleaved-caspase-3 and TUNEL), according to treatment with Adipose Tissue-Derived Stem Cells from transgenic rats for Green Fluorescent Protein (rASC-GFP), in topic and autologous grafted ovary

From: Does adipose tissue-derived stem cell therapy improve graft quality in freshly grafted ovaries?

  Topic Graft
  Vehicle rASC-GFP Vehicle rASC-GFP
VEGF 13.58 ± 4.4 27.13 ± 11.1* 25.46 ± 9.4 41.9 ± 11.7
Ki67 2.46 ± 0.55 2.12 ± 0.7 2.44 ± 1.5 1.72 ± 0.38
Caspase-3 4.23 ± 2.5 6.39 ± 2.9 6.97 ± 5.6 6.18 ± 3.44
TUNEL 0.03 ± 0.03 0.04 ± 0.08 0.13 ± 0.12 0.04 ± 0.05
  1. Data are shown as percentage of positively stained follicle cells per area (arbitrary unity/mm2). VEGF Vascular Endothelial Grown Factor, TUNEL Terminal deoxynucleotidyl transferase (TdT)-mediated dUTP nick-end
  2. Data were shown in mean ± SD; Student t-test; *p = 0.0352 vs. Vehicle