Table 7 Assignment of steroid hormone metabolites to their main reference
Full trivial name | Reference | Analyzed enzyme system |
|---|---|---|
Androgen metabolites | ||
Androsterone | Androstenedione, testosterone, 5α-dihydrotestosterone, dehydroepiandrosterone | CYP17A1, POR, SRD5A2, HSD17B3 |
Etiocholanolone | Testosterone, dehydroepiandrosterone | CYP17A1, POR, SRD5A2, HSD17B3 |
11β-Hydroxy-androsterone | 11β-hydroxy-androstenedione, cortisol | |
Dehydroepiandrosterone | Dehydroepiandrosterone | HSD3B2 |
5-Androstene-3β,17β-diol | Testosterone, dehydroepiandrosterone | |
5-Androstene-3β,17β-triol | Testosterone, dehydroepiandrosterone | |
16α-Hydroxy-dehydroepiandrosterone | Dehydroepiandrosterone | |
5-Androstene-3β,16α,17β-triol | Testosterone, dehydroepiandrosterone | |
11β-Hydroxy-etiocholanolone | Testosterone, dehydroepiandrosterone, cortisol | |
11-Oxo-etiocholanolone | Testosterone, dehydroepiandrosterone, cortisol | |
Testosterone | Testosterone | |
5α-Dihydrotestosterone | Testosterone | |
Oestrogen metabolites | ||
Estriol | Estradiol | |
17β-Estradiol | Estradiol | |
Progesterone metabolites | ||
Pregnenolone | Pregnenolone | |
17-Hydroxypregnanolone | 17-Hydroxy-progesterone | CYP17A1, POR |
Pregnanediol | Pregnenolone | POR |
Pregnanetriol | 17-Hydroxy-progesterone | CYP21A2, POR |
11-Oxopregnanetriol | 17-Hydroxy-progesterone | CYP21A2 |
5-Pregnene-3β,16α,17,20α-triol | 17-Hydroxy-pregnenolone | HSD3B2 |
11-Deoxysteroid hormone metabolites | ||
Tetrahydro-11-deoxycortisol | 11-Deoxycortisol | CYP11B1 |
Tetrahydro-11-deoxycorticosterone | Corticosterone | |
Corticosterone metabolites | ||
Tetrahydrocorticosterone | 11-Deoxycorticosterone | CYP17A1, POR, SRD5A2 |
5α-Tetrahydrocorticosterone | 11-Deoxycorticosterone | CYP17A1, POR, SRD5A2 |
Tetrahydro-11-dehydrocorticosterone | Corticosterone | CYP17A1, POR |
Tetrahydroaldosterone | Aldosterone | |
Cortisol metabolites | ||
Cortisol | Cortisol | HSD11B2 |
Tetrahydrocortisol | Cortisol | CYP21A2, CYP11B1, CYP17A1, HSD3B2, POR, HSD11B2, H6PDH, HSD17B3 |
5α-Tetrahydrocortisol | Cortisol | CYP21A2, CYP11B1, CYP17A1, HSD3B2, POR, HSD11B2, H6PDH, HSD17B3, SRD5A2 |
α-Cortol | Cortisol | HSD11B2 |
β-Cortol | Cortisol | HSD11B2 |
20α-Dihydrocortisol | Cortisol | |
6β-Hydroxycortisol | Cortisol | |
18-Hydroxycortisol | Cortisol | |
Cortisone metabolites | ||
Cortisone | Cortisol, cortisone | HSD11B2 |
Tetrahydrocortisone | Cortisol, cortisone | CYP21A2, CYP11B1, CYP17A1, HSD3B2, POR, HSD11B2, H6PDH, HSD17B3 |
α-Cortolone | Cortisol, cortisone | HSD11B2 |
β-Cortolone | Cortisol, cortisone | HSD11B2 |
20α-Dihydrocortisone | Cortisol, cortisone | |
20β-Dihydrocortisone | Cortisol, cortisone | |