Skip to main content

Table 7 Assignment of steroid hormone metabolites to their main reference

From: Gestation-specific reference intervals for comprehensive spot urinary steroid hormone metabolite analysis in normal singleton pregnancy and 6 weeks postpartum

Full trivial name Reference Analyzed enzyme system
Androgen metabolites
 Androsterone Androstenedione, testosterone, 5α-dihydrotestosterone, dehydroepiandrosterone CYP17A1, POR, SRD5A2, HSD17B3
 Etiocholanolone Testosterone, dehydroepiandrosterone CYP17A1, POR, SRD5A2, HSD17B3
 11β-Hydroxy-androsterone 11β-hydroxy-androstenedione, cortisol  
 Dehydroepiandrosterone Dehydroepiandrosterone HSD3B2
 5-Androstene-3β,17β-diol Testosterone, dehydroepiandrosterone  
 5-Androstene-3β,17β-triol Testosterone, dehydroepiandrosterone  
 16α-Hydroxy-dehydroepiandrosterone Dehydroepiandrosterone  
 5-Androstene-3β,16α,17β-triol Testosterone, dehydroepiandrosterone  
 11β-Hydroxy-etiocholanolone Testosterone, dehydroepiandrosterone, cortisol  
 11-Oxo-etiocholanolone Testosterone, dehydroepiandrosterone, cortisol  
 Testosterone Testosterone  
 5α-Dihydrotestosterone Testosterone  
Oestrogen metabolites
 Estriol Estradiol  
 17β-Estradiol Estradiol  
Progesterone metabolites
 Pregnenolone Pregnenolone  
 17-Hydroxypregnanolone 17-Hydroxy-progesterone CYP17A1, POR
 Pregnanediol Pregnenolone POR
 Pregnanetriol 17-Hydroxy-progesterone CYP21A2, POR
 11-Oxopregnanetriol 17-Hydroxy-progesterone CYP21A2
 5-Pregnene-3β,16α,17,20α-triol 17-Hydroxy-pregnenolone HSD3B2
11-Deoxysteroid hormone metabolites
 Tetrahydro-11-deoxycortisol 11-Deoxycortisol CYP11B1
 Tetrahydro-11-deoxycorticosterone Corticosterone  
Corticosterone metabolites
 Tetrahydrocorticosterone 11-Deoxycorticosterone CYP17A1, POR, SRD5A2
 5α-Tetrahydrocorticosterone 11-Deoxycorticosterone CYP17A1, POR, SRD5A2
 Tetrahydro-11-dehydrocorticosterone Corticosterone CYP17A1, POR
 Tetrahydroaldosterone Aldosterone  
Cortisol metabolites
 Cortisol Cortisol HSD11B2
 Tetrahydrocortisol Cortisol CYP21A2, CYP11B1, CYP17A1, HSD3B2, POR, HSD11B2, H6PDH, HSD17B3
 5α-Tetrahydrocortisol Cortisol CYP21A2, CYP11B1, CYP17A1, HSD3B2, POR, HSD11B2, H6PDH, HSD17B3, SRD5A2
 α-Cortol Cortisol HSD11B2
 β-Cortol Cortisol HSD11B2
 20α-Dihydrocortisol Cortisol  
 6β-Hydroxycortisol Cortisol  
 18-Hydroxycortisol Cortisol  
Cortisone metabolites
 Cortisone Cortisol, cortisone HSD11B2
 Tetrahydrocortisone Cortisol, cortisone CYP21A2, CYP11B1, CYP17A1, HSD3B2, POR, HSD11B2, H6PDH, HSD17B3
 α-Cortolone Cortisol, cortisone HSD11B2
 β-Cortolone Cortisol, cortisone HSD11B2
 20α-Dihydrocortisone Cortisol, cortisone  
 20β-Dihydrocortisone Cortisol, cortisone