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Table 6 Comparison of demographic and clinical characteristics between subgroups of the day 5 ET group

From: Progesterone elevation on the day of human chorionic gonadotropin administration adversely affects the outcome of IVF with transferred embryos at different developmental stages

Parametera Serum P levels (ng/ml), day 5 ET P-value*
  <1.75 ≥1.75  
No. of fresh cycles 1066 80  
Female age (years) 29.5 ± 4.4 31.5 ± 5.2 0.002
BMI (kg/m2) 22.60 ± 3.31 21.95 ± 2.59 0.036
Basal FSH (IU/L) 6.61 ± 1.57 6.53 ± 1.83 NS
Total dose of Gn (IU) 1760.0 ± 635.5 2114.1 ± 680.7 <0.001
Serum E2 (pg/ml), hCG day 7583.3 ± 2595.8 9200.6 ± 3038.1 <0.001
Serum LH (IU/L), hCG day 1.6 ± 0.7 1.5 ± 0.7 NS
Endometrial thickness (mm), hCG day 12.2 ± 2.3 12.1 ± 2.5 NS
No. of oocytes retrieved 17.9 ± 5.0 19.7 ± 4.9 0.003
No. of 2PN oocytes 13.1 ± 3.8 14.4 ± 4.3 0.014
No. of 2PN cleavage embryos 12.9 ± 3.8 14.2 ± 4.3 0.003
No. of available embryos 9.7 ± 3.8 9.9 ± 4.8 0.031
Fertilization rate (%) 74.4 73.5 NS
Cleavage rate (%) 98.5 99.1 NS
No. of transferred embryos 1.08 ± 0.27 1.19 ± 0.39 0.017
ET with top-quality blastocyst (%) 58.7 52.7 NS
Implantation rate (%) 46.2 29.5 0.002
CPR (%) 41.4 21.3 <0.001
  1. Note: Day 5 ET subgroups according progesterone cut-off levels: <1.75 ng/ml, ≥1.75 ng/ml; NS = not statistically significant
  2. aAll values are presented as the mean ± SD or count (%)
  3. *Differences between subgroups were determined using Student’s t-test or the Mann–Whitney U test for continuous variables and the chi-square test or Fisher’s exact test for categorical variables