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Table 3 Clinical outcome in cohort A: hCG administration on day 3

From: Intrauterine administration of human chorionic gonadotropin does not improve pregnancy and life birth rates independently of blastocyst quality: a randomised prospective study

 

Transfer with top blastocysts

Transfer with non-top blastocysts

Characteristics

hCG (n = 48)

culture medium (n = 49)

P-Value

hCG (n = 41)

culture medium (n = 44)

P-Value

Female age (years) mean ± s.d. (range)

35.3 ± 4.2 (22–42)

34.9 ± 5.0 (25–42)

0.641

37.0 ± 3.9 (30–43)

36.1 ± 5.0 (25–43)

0.380

Endometrium height (mm) mean ± s.d.

11.0  ± 2.6

10.8  ± 2.4

0.817

11.6  ± 2.2

10.8  ± 1.9

0.110

No. Embryos transferred Embryos / ET mean ± s.d.

75 1.6 ± 0.5

76 1.6 ± 0.5

0.911

69 1.7 ± 0.5

77 1.8 ± 0.5

0.522

Proportion of difficult ETs

10.4 %

8.2 %

0.702

12.2 %

9.1 %

0.642

No. Pregnancies (PR)

29 (60.4 %)

32 (65.3 %)

0.618

13 (31.7 %)

13 (29.5 %)

0.829

No. Clinical pregnancies (cPR)

25 (52.1 %)

28 (57.1 %)

0.617

8 (19.5 %)

9 (20.5 %)

0.914

No. Implanted embryos (IR)

30 (40.0 %)

32 (42.1 %)

0.793

11 (15.9 %)

12 (15.6 %)

0.953

No. Births (LBR)

24 (50.0 %)

26 (53.1 %)

0.763

7 (17.1 %)

8 (18.2 %)

0.893

No. Babies born

27

30

 

9

9

 

No. Miscarriages (MR)

1 (2.1 %)

2 (4.1 %)

0.570

1 (2.4 %)

1 (2.3 %)

0.960

  1. Ranges or percentages respectively are given in brackets, s.d.: standard deviation
  2. IVF characteristics and clinical outcome of cohort A. Miscarriage rate was defined as pregnancy loss after the detection of foetal heartbeat