Changes in estrone and estradiol levels during follicle development: a retrospective large-scale study

Table 3 E2 and FSH concentrations in the three age groups, classified according to follicle size

Diameter of the largest follicle	Serum E2 (pg/mL) measured by iE2 reagent			Serum FSH (mIU/mL)
Diameter of the largest follicle	(n = 9088)			(n = 9088)
	Age <38 year	Age 38–40 year	Age >40 year	Age <38 year	Age 38–40 year	Age >40 year
11 mm	68.0 ± 34.7^a	71.0 ± 40.4^a	86.8 ± 51.8^a	8.6 ± 2.4^b	9.5 ± 4.6	10.9 ± 6.8^b
12 mm	80.4 ± 41.8^a	84.7 ± 42.9^a	102.8 ± 53.5^a	8.4 ± 2.4^a	8.8 ± 3.0^a	11.1 ± 7.1^a
13 mm	87.3 ± 42.6^a	96.7 ± 44.6^a	116.1 ± 61.2^a	7.9 ± 2.3^a	8.3 ± 3.2^a	10.3 ± 7.0^a
14 mm	100.3 ± 51.7^c	115.8 ± 58.6^c	126.1 ± 64.0^c	7.4 ± 1.9^c	8.5 ± 3.5^c	9.9 ± 8.5^c
15 mm	132.6 ± 64.2^d	150.2 ± 66.5^d	170.6 ± 76.5^d	7.3 ± 2.3^c	8.3 ± 3.7^c	8.8 ± 4.3^c
16 mm	160.0 ± 77.9^a	177.0 ± 78.2^a	197.4 ± 79.5^a	7.1 ± 2.5^a	7.7 ± 3.6^a	9.0 ± 5.2^a
17 mm	200.2 ± 85.7^b	216.5 ± 78.5	222.3 ± 86.6^b	6.8 ± 2.2^d	7.7 ± 3.1^d	8.8 ± 6.0^d
18 mm	229.2 ± 85.4^b	233.5 ± 88.9	247.0 ± 82.2^b	6.6 ± 2.3^d	7.2 ± 2.8^d	8.5 ± 5.1^d
19 mm	249.6 ± 78.0	256.0 ± 79.5	261.0 ± 83.5	6.3 ± 2.3^a	6.8 ± 2.3^a	8.3 ± 6.4^a
20 mm	275.6 ± 95.2	285.1 ± 88.0	280.6 ± 92.0	6.5 ± 2.2^a	6.8 ± 2.3^a	7.8 ± 4.0^a

Data are presented as mean ± standard deviation
^aSignificant differences were found between the <38 year group and the >40 year group, as well as between the 38–40 year group and the >40 year group (P < 0.01)
^bSignificant differences were found between the <38 year group and the >40 year group (P < 0.01)
^cSignificant differences were found between the <38 year group and the 38–40 year group, as well as between the <38 year group and the >40 year group (P < 0.01)
^dSignificant differences were found among all three age groups (P < 0.01)
E2 estradiol, FSH follicle-stimulating hormone, iE2 reagent ST AIA-PACK iE2 reagent

ISSN: 1477-7827